CAS 80-92-2

Pregnanediol

Description:

Pregnanediol is a steroidal compound that serves as a significant metabolite of progesterone, a key hormone in the reproductive system. It is characterized by its chemical structure, which includes two hydroxyl (-OH) groups, making it a diol. Pregnanediol is typically found in the form of a colorless to pale yellow liquid or solid, depending on its purity and conditions. It is soluble in organic solvents but has limited solubility in water. This compound plays a crucial role in various biological processes, particularly in the metabolism of steroids and the regulation of reproductive functions. In clinical settings, pregnanediol levels can be measured to assess ovarian function and monitor pregnancy. Additionally, it is used in research to study hormonal pathways and the effects of steroid hormones on the body. Due to its biological significance, understanding the properties and behavior of pregnanediol is essential in both pharmacology and endocrinology.

Formula:C₂₁H₃₆O₂

InChI:InChI=1/C21H36O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-19,22-23H,4-12H2,1-3H3/t13-,14-,15-,16-,17-,18-,19-,20+,21-/m0/s1

InChI key:InChIKey=YWYQTGBBEZQBGO-BERLURQNSA-N

SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@H](C)O)(CC4)[H])[H])(CC[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Synonyms:

(3alpha,5beta,20S)-pregnane-3,20-diol
(3alpha,5beta,20alpha)-Pregnane-3,20-diol
(3α,5β,20S)-Pregnane-3,20-diol
17-(1-hydroxyethyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
3-alpha,20-alpha-Dihydroxy-5-beta-pregnane
3alpha,20alpha-Dihydroxy-5beta-pregnane
3α,20α-Dihydroxy-5β-pregnane
5-beta-Pregnane, 3-alpha,20-alpha-dihydroxy-
5-beta-Pregnane-3-alpha, 20-alpha-diol
5-Β-Pregnano-3-Α-20-Α-Diol
5-β-Pregnan-3-α,20-α-diol
5beta-Pregnane, 3alpha,20alpha-dihydroxy-
5beta-Pregnane-3alpha,20alpha-diol (8CI)
5β-Pregnane-3α,20α-diol
Brn 3083715
Diol
Diol (6CI,7CI)
Nsc 1612
Nsc 47462
Pregnandiol
Pregnandiol [JAN]
Pregnane-3,20-diol
Pregnane-3,20-diol, (3-alpha,5-beta,20S)- (9CI)
Pregnane-3,20-diol, (3alpha,5beta,20S)- (9CI)
Pregnane-3,20-diol, (3α,5β,20S)-
Pregnane-3alpha,20alpha-diol
Pregnanediol
Unii-Jr3Jd1Y22C
4-06-00-06111 (Beilstein Handbook Reference)
5SS-PREGNANE-3ALPHA,20ALPHA-DIOL
5-BETA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL
(8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol
Pregnane-3,20-diol, (3a,5b,20S)- (9CI)
3a,20a-Dihydroxy-5pregnane
THA
5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL
(3α,5β),20S)-
(3a,5),20S)-Pregnane-3,20-diol
5b-Pregnane-3a,20a-diol (8CI)
5-Pregnane-3alpha,20alpha-diol
3-alpha,20-alpha-dihydroxy-5-beta-pregnan
3ALPHA,20ALPHA-Dihydroxy-5B-pregnane
(20S)-3α,20-Dihydroxy-5β-pregnane
(20S)-5β-Pregnan-3α,20-diol
Pregnane-3,20-diol, (3.alpha.,5.beta.,20S)-
5BETA-PREGNAN-3A,20A-DIOL
5β-Pregnane-3α,20α-diol-d5
5BETA-PREGNANE-3ALPHA 20ALPHA-DIOL 98+%
TETRAHYDRO COMPOUND ''A''
See more synonyms

Purity (%)

100

Found 12 products.

+ Info
5β-Pregnane-3α,20α-diol
CAS:
- 80-92-2
Formula:C₂₁H₃₆O₂
Purity:>98.0%(HPLC)
Color and Shape:White to Almost white powder to crystal
Molecular weight:320.52
Ref: 3B-P0678
100mg
55.00€
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1g
320.00€
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5β-Pregnane-3α,20α-diol
CAS:
- 80-92-2
Formula:C₂₁H₃₆O₂
Purity:95%
Color and Shape:Solid
Molecular weight:320.5093
Ref: IN-DA003472
100mg
187.00€
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250mg
286.00€
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5β-Pregnane-3α,20α-diol
CAS:
- 80-92-2
5β-Pregnane-3α,20α-diol
Formula:C₂₁H₃₆O₂
Purity:>95%
Molecular weight:320.52
Ref: 54-OR1023940
25mg
77.00€
VAT not included
100mg
240.00€
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250mg
374.00€
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1g
1,301.00€
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Pregnanediol
CAS:
- 80-92-2
Pregnanediol
Formula:C₂₁H₃₆O₂
Purity:≥98%
Molecular weight:320.51
Ref: 54-BUP11432
5mg
53.00€
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10mg
80.00€
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25mg
143.00€
VAT not included
50mg
218.00€
VAT not included
100mg
353.00€
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Pregnanediol
CAS:
- 80-92-2
Formula:C₂₁H₃₆O₂
Molecular weight:320.52
Ref: 4Z-P-462005
5mg
To inquire
100mg
To inquire
10mg
498.00€
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25mg
810.00€
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50mg
1,132.00€
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Pregnanediol (5β-Pregnane-3α,20(S)-diol)
CAS:
- 80-92-2
Color and Shape:Neat
Ref: 61-FOR0222.14
10mg
To inquire
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Pregnanediol (5β-Pregnane-3α,20(S)-diol)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 80-92-2
Formula:C₂₁H₃₆O₂
Color and Shape:Neat
Molecular weight:320.51
Ref: 86-MM0222.14
25mg
To inquire
100mg
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Pregnanediol (5β-Pregnane-3α,20(S)-diol)
CAS:
- 80-92-2
Color and Shape:Neat
Ref: LP-PRO-2333
10mg
To inquire
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Pregnanediol
CAS:
- 80-92-2
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of progesterone by reduction at C5, C3, and C20 position.
Formula:C₂₁H₃₆O₂
Purity:98% - 99.91%
Color and Shape:Solid
Molecular weight:320.51
Ref: TM-T1688
5mg
34.00€
VAT not included
10mg
54.00€
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25mg
92.00€
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50mg
147.00€
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100mg
245.00€
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5-β-Pregnane-3-α,20-α-diol
CAS:
- 80-92-2
Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),
Formula:C₂₁H₃₆O₂
Color and Shape:Neat
Molecular weight:320.51
Ref: TR-P705130
10mg
191.00€
VAT not included
25mg
347.00€
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100mg
951.00€
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5β-Pregnane-3α,20α-diol-d5
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 80-92-2
Applications Labelled 5β-Pregnane-3α,20α-diol, a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937); Okuda, A. et al.: J. Biol. Chem., 259, 7519 (1984); Russell, D. et al.: Biochemistry, 31, 4737 (1992); Kondo, K. et al.: Eur. J. Biochem.; 219, 357 (1994); Westerbacka, J. et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003);
Formula:C₂₁H₃₁D₅O₂
Color and Shape:Neat
Molecular weight:325.54
Ref: TR-P705132
1mg
377.00€
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10mg
2,496.00€
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+ Info
5β-Pregnane-3α,20α-diol
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 80-92-2
5β-Pregnane-3α,20α-diol is a human metabolite of estradiol that has been found to be an active inhibitor of the enzyme activity of GABA transaminase. It has been shown to have therapeutic potential in the prevention and treatment of cervical cancer, as well as other cancers. 5β-Pregnane-3α,20α-diol has also been found to inhibit ovarian activity. The diagnostic method for this metabolite is based on monoclonal antibody (MAb) reactivity with immunosorbent assay (ELISA) and gas chromatography/mass spectrometry (GC/MS). Women who have high values for this metabolite may be at risk for uterine cancer or breast cancer.
Formula:C₂₁H₃₆O₂
Purity:Min. 98 Area-%
Color and Shape:White Powder
Molecular weight:320.51 g/mol
Ref: 3D-FP27150
100mg
240.00€
VAT not included
250mg
361.00€
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500mg
452.00€
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1g
804.00€
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2g
1,399.00€
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