CAS 80012-44-8

Epinastine hydrochloride

Description:

Epinastine hydrochloride is an antihistamine used primarily for the treatment of allergic conjunctivitis and other allergic conditions. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a compound involved in allergic responses. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for ophthalmic formulations. Epinastine hydrochloride exhibits a relatively low molecular weight and has a specific chemical structure that contributes to its pharmacological activity. Its mechanism of action not only alleviates symptoms such as itching and redness but also has anti-inflammatory properties. The compound is typically administered in the form of eye drops, allowing for localized treatment with minimal systemic absorption. Safety and efficacy profiles have been established through clinical studies, and it is generally well-tolerated, with common side effects being mild and transient. As with any medication, it is essential to follow dosing guidelines and consult healthcare professionals for appropriate use.

Formula: C₁₆H₁₆ClN₃

InChI: InChI=1/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChI key: InChIKey=VKXSGUIOOQPGAF-UHFFFAOYSA-N

SMILES: NC=1N2C(C=3C(CC=4C2=CC=CC4)=CC=CC3)CN1.Cl

Synonyms:

• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1)
• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, monohydrochloride
• 3-Amino-9,13b-Dihydro-1h-Dibenz[C,F]Imidazo[1,5-A]Azepine Hydrochloride
• 9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (1:1)
• Alesion
• Elestat
• Epinastin Hcl
• Epinastine hcl
• Wal 801Cl
• Epinastine Hydrochloride
• Epinastine hydrochloride

Epinastine Hydrochloride

CAS: 108929-04-0, 80012-44-8

Formula: C₁₆H₁₅N₃·HCl

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 285.78

Ref: 3B-E0799

Epinastine

CAS: 80012-44-8

Epinastine hydrochloride is a kinase inhibitor that has been traditionally used in Chinese medicine. It has been found to have anti-cancer properties, specifically inhibiting the growth of human cancer cells by blocking the cell cycle. Epinastine hydrochloride has been shown to inhibit the proliferation of leukemia cells and other human cancer cell lines. This drug acts as an inhibitor of protein kinases, which are enzymes that regulate cellular processes such as proliferation, differentiation, and apoptosis. Additionally, epinastine hydrochloride has been observed to reduce the amount of protein in urine in patients with certain types of cancer. Overall, epinastine hydrochloride shows promise as a potential therapy for various types of cancers.

Formula: C₁₆H₁₅N₃

Purity: Min. 95%

Molecular weight: 249.31 g/mol

Ref: 3D-FDA01244