CAS 80012-44-8: Epinastine hydrochloride

Description: Epinastine hydrochloride is an antihistamine used primarily for the treatment of allergic conjunctivitis and other allergic conditions. It functions as a selective H1 receptor antagonist, effectively blocking the action of histamine, a compound involved in allergic responses. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for ophthalmic formulations. Epinastine hydrochloride exhibits a relatively low molecular weight and has a specific chemical structure that contributes to its pharmacological activity. Its mechanism of action not only alleviates symptoms such as itching and redness but also has anti-inflammatory properties. The compound is typically administered in the form of eye drops, allowing for localized treatment with minimal systemic absorption. Safety and efficacy profiles have been established through clinical studies, and it is generally well-tolerated, with common side effects being mild and transient. As with any medication, it is essential to follow dosing guidelines and consult healthcare professionals for appropriate use.

Formula: C₁₆H₁₅N₃·ClH

InChI: InChI=1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H

InChI key: InChIKey=VKXSGUIOOQPGAF-UHFFFAOYSA-N

SMILES: Cl.N1=C(N)N2C=3C=CC=CC3CC=4C=CC=CC4C2C1

Synonyms:

• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1)
• 1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, monohydrochloride
• 3-Amino-9,13b-Dihydro-1h-Dibenz[C,F]Imidazo[1,5-A]Azepine Hydrochloride
• 9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (1:1)
• Alesion
• Elestat
• Epinastin Hcl
• Epinastine hcl
• Wal 801Cl
• Epinastine Hydrochloride
• Epinastine hydrochloride

Epinastine Hydrochloride

CAS: 108929-04-0 80012-44-8

• Formula: C₁₆H₁₅N₃·HCl
• Purity: >98.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 285.78

Epinastine

CAS: 80012-44-8

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• Formula: C₁₆H₁₅N₃
• Purity: Min. 95%
• Molecular weight: 249.31 g/mol