CAS 80382-23-6

Loxoprofen sodium

Description:

Loxoprofen sodium is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is a sodium salt of loxoprofen, which is a propionic acid derivative. The substance is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, leading to a reduction in the synthesis of prostaglandins, which are mediators of pain and inflammation. Loxoprofen sodium is typically administered orally and is known for its rapid absorption and onset of action. It is often used to treat conditions such as osteoarthritis, rheumatoid arthritis, and postoperative pain. The drug is generally well-tolerated, but like other NSAIDs, it may cause gastrointestinal side effects, cardiovascular risks, and renal impairment in some patients. Its chemical structure includes a chiral center, which contributes to its pharmacological activity. As with any medication, it is essential to use loxoprofen sodium under medical supervision to manage potential side effects and interactions with other drugs.

Formula: C₁₅H₁₈O₃·Na

InChI: InChI=1S/C15H18O3.Na/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);

InChI key: InChIKey=IEPGDDWZDRJSIT-UHFFFAOYSA-N

SMILES: C(C1=CC=C(C(C(O)=O)C)C=C1)C2C(=O)CCC2.[Na]

Synonyms:

• Benzeneacetic acid, alpha-methyl-4-((2-oxocyclopentyl)methyl)-, sodium salt, dihydrate
• Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt
• Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-, sodium salt (1:1)
• CS 600 (antiinflammatory)
• Cs-600
• LXP
• Loxonin
• Loxoprofen sodium dihydrate
• Sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate
• Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate
• Sodium 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoate
• Sodium 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoate Hydrate (1:1:2)
• Sodium loxoprofen
• alpha-Methyl-4-((2-oxocyclopentyl)methyl)benzeneacetate sodium salt dihydrate

Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate

CAS: 80382-23-6

Formula: C₁₅H₁₇NaO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 268.2835

Ref: IN-DA008MSD

Loxoprofen sodium

CAS: 80382-23-6

Loxoprofen sodium

Formula: C₁₅H₁₇NaO₃

Purity: ≥98%

Molecular weight: 268.2834

Ref: 54-BUP14153

Loxoprofen sodium

CAS: 80382-23-6

Loxoprofen sodium

Formula: C₁₅H₁₇NaO₃

Purity: >99%

Molecular weight: 268.28

Ref: 54-OR1030194

Loxoprofen sodium salt

CAS: 80382-23-6

Formula: C₁₅H₂₁NaO₅

Molecular weight: 304.31

Ref: 7W-GP4329

Loxoprofen Sodium

CAS: 80382-23-6

Color and Shape: Neat

Ref: 86-MM3940.00

Loxoprofen sodium

CAS: 80382-23-6

Loxoprofen sodium is a COX-1/COX-2 inhibitor (IC50: 6.5/13.5 μM) used orally for anti-inflammatory and antitumor effects.

Formula: C₁₅H₁₇NaO₃

Purity: 99.88%

Color and Shape: White Solid

Molecular weight: 268.2834

Ref: TM-T0463L

Loxoprofen sodium

CAS: 80382-23-6

Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate

Formula: C₁₅H₁₇NaO₃

Purity: 97%

Molecular weight: 268.28

Ref: IN-DG22681

Loxoprofen Sodium

CAS: 80382-23-6

Formula: C₁₅H₁₈O₃Na

Molecular weight: 246.3 : 23.0

Ref: ST-EA-CP-L133004

Loxoprofen sodium

CAS: 80382-23-6

Inhibitor of prostaglandin production; non-steroidal COX inhibitor

Formula: C₁₅H₁₇NaO₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 268.28 g/mol

Ref: 3D-FL24954

Loxoprofen sodium - Bio-X ™

CAS: 80382-23-6

Loxoprofen is a non-steroidal anti-inflammatory drug that belongs to the group of propionic acid derivatives. It can be used for the treatment of pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal disorders. Its therapeutic effects are attributed to inhibition of cyclooxygenases 1 and 2 (COX-1 and COX-2) enzymes.

Formula: C₁₅H₁₈O₃•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 269.29 g/mol

Ref: 3D-BL164648

Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate

CAS: 80382-23-6

Formula: C₁₅H₁₇NaO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 268.288

Ref: 10-F498958

Loxoprofen Sodium (Mixture of diastereomers)

Controlled Product

CAS: 80382-23-6

Applications A non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Formula: C₁₅H₁₇O₃·Na

Color and Shape: Neat

Molecular weight: 268.28

Ref: TR-L472900

Loxoprofen Sodium Salt Dihydrate

CAS: 226721-96-6, 68767-14-6, 80382-23-6

Formula: C₁₅H₁₇NaO₃·2H₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 304.32

Ref: 3B-L0252