CAS 80486-69-7

(6alpha,11beta,16alpha,17alpha)-17-{[(chloromethyl)sulfanyl]carbonyl}-6,9-difluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate

Description:

The chemical substance with the name "(6alpha,11beta,16alpha,17alpha)-17-{[(chloromethyl)sulfanyl]carbonyl}-6,9-difluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl propanoate" and CAS number 80486-69-7 is a synthetic steroid derivative. It features a complex structure characterized by multiple functional groups, including a chloromethyl sulfanyl group and a propanoate ester. The presence of fluorine atoms indicates potential modifications to its biological activity and stability. The compound is likely to exhibit hormonal activity due to its steroid backbone, which may influence various physiological processes. Its specific stereochemistry, denoted by the alpha and beta designations, suggests that it may interact with biological receptors in a particular manner, potentially affecting its efficacy and potency. The compound's unique combination of functional groups and structural features may also contribute to its solubility, reactivity, and overall pharmacological profile. Further studies would be necessary to fully elucidate its biological effects and potential applications in medicinal chemistry.

Formula: C₂₅H₃₁ClF₂O₅S

InChI: InChI=1/C25H31ClF2O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1

Synonyms:

• (6a,11b,16a,17a)-17-(((Chloromethyl)thio)carbonyl)-6,9-difluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-yl Propionate
• (6a,11b,16a,17a)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic Acid S-(Chloromethyl) Ester
• androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, S-(chloromethyl) ester, (6alpha,11beta,16alpha,17alpha)-
• Cloticasone Propionate

Chloro Fluticasone Propionate

CAS: 80486-69-7

Formula: C₂₅H₃₁ClF₂O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 517.02

Ref: 4Z-F-0929

Cloticasone Propionate

Controlled Product

CAS: 80486-69-7

Applications An intermediate in the synthesis of Fluticasone Propionate.
References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Formula: C₂₅H₃₁ClF₂O₅S

Color and Shape: Neat

Molecular weight: 517.03

Ref: TR-C369160

Cloticasone Propionate-d3

Controlled Product

CAS: 80486-69-7

Applications An intermediate in the synthesis of Fluticasone Propionate.
References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Formula: C₂₅D₃H₂₈ClF₂O₅S

Color and Shape: Neat

Molecular weight: 520.044

Ref: TR-C369162

Chloro Fluticasone Propionate

CAS: 80486-69-7

Formula: C₂₅H₃₁ClF₂O₅S

Molecular weight: 517.02

Ref: ST-EA-CP-F23014