CAS 81131-70-6
:Pravastatin sodium
Description:
Pravastatin sodium is a synthetic lipid-lowering agent belonging to the statin class, primarily used to manage hyperlipidemia and reduce the risk of cardiovascular diseases. It functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol biosynthesis in the liver, thereby lowering total cholesterol and low-density lipoprotein (LDL) levels. This compound is characterized by its relatively high solubility in water, which enhances its bioavailability. Pravastatin sodium is typically administered orally and is known for its favorable safety profile, with a lower incidence of muscle-related side effects compared to some other statins. Its pharmacokinetics involve extensive hepatic uptake and metabolism, with a significant portion of the drug being excreted unchanged in the urine. Additionally, pravastatin has been shown to possess anti-inflammatory properties and may improve endothelial function, contributing to its cardiovascular protective effects. As with any medication, it is essential to monitor for potential interactions and contraindications, particularly in patients with liver impairment or those taking other medications that may affect statin metabolism.
Formula:C23H36O7·Na
InChI:InChI=1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1
InChI key:InChIKey=RNAREGLVKQKRSG-IYNICTALSA-N
SMILES:C(C[C@H](C[C@H](CC(O)=O)O)O)[C@@H]1[C@]2([C@@H](OC([C@H](CC)C)=O)C[C@H](O)C=C2C=C[C@@H]1C)[H].[Na]
Synonyms:- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, monosodium salt, [1S-[1α(βS*,δS*),2α,6α,8β(R*),8aα]]-
- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, monosodium salt, (βR,δR,1S,2S,6S,8S,8aR)-
- 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt (1:1), (βR,δR,1S,2S,6S,8S,8aR)-
- 3β-Hydroxycompactin sodium salt
- Cs 514
- Elisor
- Epastatin sodium
- Eptastatin sodium
- Lipidal
- Lipostat
- Liprevil
- Mevalotin
- Mevan
- Oliprevin
- Prava
- Pravachol
- Pravacol
- Pravaselect
- Pravasin
- Pravasine
- Pravastatin Sodium
- Pravastatin sodium salt
- Pravastin
- Pravator
- Selectin
- Selektine
- Selipran
- Sodium pravastatin
- Sq 31000
- Vasten
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Found 17 products.
Pravastatin Sodium
CAS:Formula:C23H35NaO7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:446.52Pravastatin Sodium
CAS:Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoiFormula:C23H36O7Color and Shape:White Yellow Crystalline PowderMolecular weight:424.2461Pravastatin Sodium
CAS:(3R,5R)-3,5-Dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid, sodium saltFormula:C23H35NaO7Purity:98%Molecular weight:446.511-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt (1:1), (βR,δR,1S,2S,6S,8S,8aR)-
CAS:Formula:C23H35NaO7Purity:98%Color and Shape:SolidMolecular weight:446.5096Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purity:97.14% - 99.97%Color and Shape:White Crystalline PowderMolecular weight:446.52Pravastatin sodium salt
CAS:Formula:C23H35O7Na·xH2OPurity:97.0 - 102.0 % (anhydrous substance)Color and Shape:White to light-yellow crystalline powderMolecular weight:446.51Pravastatin Sodium Salt
CAS:Formula:C23H35O7·NaColor and Shape:Off-White SolidMolecular weight:423.53 22.99Pravastatin Sodium
CAS:Controlled ProductFormula:C23H35O7·NaColor and Shape:White To Off-WhiteMolecular weight:446.51Pravastatin sodium
CAS:Pravastatin sodiumFormula:C23H35O7·NaPurity:98%Color and Shape:Solid-PowderMolecular weight:446.50956Pravastatin Sodium
CAS:Stability Hygroscopic
Applications A competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of Mevastatin.
References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)Formula:C23H35O7·NaColor and Shape:NeatMolecular weight:446.51Pravastatin sodium salt - Bio-X ™
CAS:Pravastatin is an HMG-CoA reductase inhibitor that is used to lower lipid levels and manage cardiovascular events such as strokes and myocardial infarction. This drug inhibits HMG-CoA reductase allowing for a reduction in the level of cholesterol.Formula:C23H35NaO7Purity:Min. 95%Color and Shape:PowderMolecular weight:446.51 g/molPravastatin sodium
CAS:HMG-CoA reductase inhibitor
Formula:C23H35NaO7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:446.51 g/molPravastatin-d9 Sodium (mixture of 2 diastereomers)
CAS:Controlled ProductApplications Pravastatin-d9 Sodium, is the labeled analogue of Pravastatin Sodium (P702000), a competitive inhibitor of HMG-CoA reductase, and bioactive metabolite of Mevastatin.
References Serizawa, N., et al.: J. Antibiot., 36, 604 (1983), Yoshino, G., et al.: Lancet, 2, 740 (1986), White, H.D, et al.: N. Engl. J. Med., 343, 317 (2000)Formula:C23D9H26O7·NaColor and Shape:NeatMolecular weight:455.56
