CAS 81265-93-2

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N6-benzoyl adenosine

Description:

2'-O-t-Butyldimethylsilyl-5'-O-(4,4'-dimethoxytrityl)-N6-benzoyl adenosine is a modified nucleoside that features several protective groups, enhancing its stability and reactivity in biochemical applications. The presence of the t-butyldimethylsilyl group at the 2' position provides protection against hydrolysis, making it useful in synthetic pathways involving RNA or DNA. The 5'-O-(4,4'-dimethoxytrityl) group serves as a protecting group for the 5' hydroxyl, facilitating the synthesis of oligonucleotides by preventing premature reactions. The N6-benzoyl modification at the adenine base enhances the nucleoside's stability and can influence its binding properties in biological systems. This compound is typically utilized in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides for research and therapeutic applications. Its structural modifications allow for improved solubility and stability, making it a valuable tool in molecular biology and biochemistry. Overall, this compound exemplifies the strategic use of protective groups in the synthesis of complex nucleoside derivatives.

Formula: C₄₄H₄₉N₅O₇Si

Synonyms:

• 5'-Dmt-2'-Tbdms-Bz-Ra

5'-O-DMT-2'-O-Tbdms-N-Bz-Adenosine

CAS: 81265-93-2

5'-O-DMT-2'-O-Tbdms-N-Bz-Adenosine

Formula: C₄₄H₄₉N₅O₇Si

Purity: 95%

Molecular weight: 787.97

Ref: 54-OR1030053

5'-O-DMT-2'-O-TBDMS-N6-Bz-adenosine

CAS: 81265-93-2

Formula: C₄₄H₄₉N₅O₇Si

Purity: 98%

Color and Shape: Solid

Molecular weight: 787.9747

Ref: IN-DA00545O

N6-Benzoyl-2''-O-tert-butyldimethylsilyl-5''-O-DMT-adenosine

CAS: 81265-93-2

Ref: 7W-GN8793

5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine

CAS: 81265-93-2

5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine, an adenosine derivative, serves as an intermediate in the synthesis of oligonucleotides.

Formula: C₄₄H₄₉N₅O₇Si

Color and Shape: Solid

Molecular weight: 787.97

Ref: TM-T37146

N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine

CAS: 81265-93-2

N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.

Formula: C₄₄H₄₉N₅O₇Si

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 787.97 g/mol

Ref: 3D-NB15297

5′-O-DMT-2′-O-TBDMS-N-Bz-Adenosine

CAS: 81265-93-2

Purity: 96%

Molecular weight: 787.989

Ref: 10-F986771