CAS 81279-39-2

5'-DMT-2'-TBDMS-ibu-rG

Description:

5'-DMT-2'-TBDMS-ibu-rG, with the CAS number 81279-39-2, is a modified nucleoside analog that features a 5'-dimethyltrityl (DMT) protective group and a 2'-tert-butyldimethylsilyl (TBDMS) group. This compound is primarily utilized in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. The presence of the DMT group allows for selective protection of the 5' hydroxyl group, facilitating the stepwise synthesis of RNA or DNA strands. The TBDMS group provides stability and protection for the 2' hydroxyl group, which is crucial for maintaining the integrity of the nucleoside during chemical reactions. This compound is characterized by its ability to enhance the solubility and stability of nucleosides, making it valuable in various biochemical applications, including gene synthesis and molecular biology research. Its structural modifications contribute to improved reactivity and compatibility in synthetic pathways, allowing for the development of more efficient and versatile nucleic acid constructs.

Formula: C₄₁H₅₁N₅O₈Si

Synonyms:

• N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine

CAS: 81279-39-2

Formula: C₄₁H₅₁N₅O₈Si

Purity: 95%

Color and Shape: Solid

Molecular weight: 769.9578

Ref: IN-DA005LEN

5-O-DMT-2-O-iBu-N-Bz-Guanosine

CAS: 81279-39-2

5-O-DMT-2-O-iBu-N-Bz-Guanosine

Purity: 95%

Molecular weight: 769.96g/mol

Ref: 54-OR1027126

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine

CAS: 81279-39-2

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides.

Formula: C₄₁H₅₁N₅O₈Si

Color and Shape: Solid

Molecular weight: 769.96

Ref: TM-T40921

5′-O-DMT-2′-O-iBu-N-Bz-Guanosine

CAS: 81279-39-2

Purity: 95%

Molecular weight: 769.971

Ref: 10-F986826

2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine

CAS: 81279-39-2

2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.

Formula: C₄₁H₅₁N₅O₈Si

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 769.96 g/mol

Ref: 3D-ND57513