CAS 81430-62-8

Formula: C35H24N8

InChI: InChI=1S/C35H24N8/c1-5-13-24(14-6-1)28-21-30(26-17-9-3-10-18-26)42-34(36-28)38-32(40-42)23-33-39-35-37-29(25-15-7-2-8-16-25)22-31(43(35)41-33)27-19-11-4-12-20-27/h1-22H,23H2

InChI key: QFTLBEGGYAFYLK-UHFFFAOYSA-N

SMILES: C1=CC=C(C=C1)C2=CC(=NC3=NC(=NN23)CC4=NN5C(=CC(=NC5=N4)C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C8

CB-0821

CAS: 81430-62-8

CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.

Formula: C₃₅H₂₄N₈

Color and Shape: Solid

Molecular weight: 556.62

Ref: TM-T210101