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CAS 81732-46-9

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Bambuterol hydrochloride

Description:
Bambuterol hydrochloride is a long-acting beta-2 adrenergic agonist primarily used in the management of asthma and chronic obstructive pulmonary disease (COPD). It functions by relaxing bronchial smooth muscle, leading to bronchodilation and improved airflow. This compound is a prodrug of terbutaline, meaning it is metabolized in the body to produce the active form. Bambuterol hydrochloride is characterized by its relatively long half-life, allowing for once-daily dosing, which enhances patient compliance. The substance is typically administered orally and is known for its ability to provide sustained relief from bronchospasm. In terms of its chemical properties, it is a quaternary ammonium compound, which contributes to its pharmacokinetic profile. The hydrochloride salt form enhances its solubility and stability. As with any medication, potential side effects may include tremors, palpitations, and headache, and it should be used with caution in patients with cardiovascular conditions. Overall, bambuterol hydrochloride represents an important therapeutic option in respiratory medicine.
Formula:C18H29N3O5·ClH
InChI:InChI=1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H
InChI key:InChIKey=LBARATORRVNNQM-UHFFFAOYSA-N
SMILES:C(CNC(C)(C)C)(O)C1=CC(OC(N(C)C)=O)=CC(OC(N(C)C)=O)=C1.Cl
Synonyms:
  • 5-[2-(Tert-Butylamino)-1-Hydroxyethyl]Benzene-1,3-Diyl Bis(Dimethylcarbamate)
  • 5-[2-(Tert-Butylamino)-1-Hydroxyethyl]Benzene-1,3-Diyl Bis(Dimethylcarbamate) Hydrochloride (1:1)
  • Bambec
  • Bambuterol HCl
  • Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1)
  • Carbamic acid, dimethyl-, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-1,3-phenylene ester, monohydrochloride
  • Kwd 2183
  • Bambuterol hydrochloride
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