CAS 82-02-0

Khellin

Description:

Khellin, with the CAS number 82-02-0, is a naturally occurring compound derived from the plant Ammi visnaga, commonly known as the toothpick herb. It is classified as a furanocoumarin, a type of organic compound that features a fused furan and coumarin structure. Khellin is known for its pharmacological properties, particularly its ability to act as a vasodilator, which can help improve blood flow and reduce blood pressure. It has also been studied for its potential therapeutic effects in treating conditions such as asthma and kidney stones. The compound is typically a white to pale yellow crystalline solid, and it is soluble in organic solvents like ethanol and chloroform but has limited solubility in water. Khellin's mechanism of action involves the inhibition of certain enzymes and modulation of calcium channels, contributing to its biological effects. Due to its natural origin and potential health benefits, khellin has garnered interest in both traditional and modern medicine. However, further research is needed to fully understand its efficacy and safety in clinical applications.

Formula: C₁₄H₁₂O₅

InChI: InChI=1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3

InChI key: InChIKey=HSMPDPBYAYSOBC-UHFFFAOYSA-N

SMILES: O(C)C=1C2=C(C(OC)=C3C1C=CO3)OC(C)=CC2=O

Synonyms:

• 4,9-Dimethoxy-7-Methylfurano(3,2-G)Chromen-5-One
• 4,9-Dimethoxy-7-methyl-5-oxo-1,8-dioxabenz[f]indene
• 4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g]-1,2-chromene
• 4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g][1]benzopyran
• 4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
• 4,9-dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one
• 5,8-Dimethoxy-2-methyl-4′,5′-furano-6,7-chromone
• 5,8-Dimethoxy-2-methyl-4′,5′-furo-6,7-chromone
• 5,8-Dimethoxy-2-methyl-6,7-furanochromone
• 5H-Furo[3,2-g][1]benzopyran-5-one, 4,9-dimethoxy-7-methyl-
• Amicardien
• Amicardine
• Amikellin
• Ammipuran
• Ammispasmin
• Ammivin
• Ammivisnagen
• Benecardin
• Benekardin
• Cardio-khellin
• Corafurone
• Coronin
• Eskel
• Gynokhellan
• Gynokhellin
• Hkelfren
• Kalangin
• Kelamin
• Kelicor
• Kelicorin
• Kellosal
• Keloid
• Khelfren
• Khelisem
• Khelline I
• Khelloyd
• Lynamine
• Medekellin
• Methafrone
• NSC 25509
• NSC 37744
• NSC 8519
• Norkel
• Simeskellina
• Vasokellina
• Visammin
• Viscardan
• Visnagalin

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Purity: >95.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 260.25

Ref: 3B-K0039

Khellin

CAS: 82-02-0

Khellin

Formula: C₁₄H₁₂O₅

Purity: ≥98%

Molecular weight: 260.24

Ref: 54-BUP06941

Khellin

CAS: 82-02-0

Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.

Formula: C₁₄H₁₂O₅

Purity: 99.89% - 99.95%

Color and Shape: Solid

Molecular weight: 260.2421

Ref: TM-T1431

Khellin

CAS: 82-02-0

Khellin

Formula: C₁₄H₁₂O₅

Purity: >95.0%

Molecular weight: 260.24

Ref: 54-OR1027456

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Purity: ≥ 95.0%

Color and Shape: White to light-yellow powder

Molecular weight: 260.24

Ref: 7W-GT8694

Khellin

CAS: 82-02-0

Khellin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₄H₁₂O₅

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 260.25

Ref: 11-6551A

Khellin (Standard)

CAS: 82-02-0

Khellin (Standard) is a reference standard for research and analysis in studies involving Khellin. Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.

Formula: C₁₄H₁₂O₅

Molecular weight: 260.2421

Ref: TM-TMSM-2272

4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 260.2421

Ref: IN-DA00G2HU

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 260.245

Ref: BP-SBP00648

Khellin

Controlled Product

CAS: 82-02-0

Applications Khellin is a compound present in the kella or picktooth fruit, used as a muscle relaxant.
References Shinde, P. et al.: Indian J. Nat. Prod. Res., 5, 40 (2014); Sztiller-Sikorska, M. et al.:

Formula: C₁₄H₁₂O₅

Color and Shape: Neat

Molecular weight: 260.24

Ref: TR-K432000

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Molecular weight: 260.25

Ref: 4Z-K-016001

Khellin

CAS: 82-02-0

Oxygen-heterocyclic compound

Formula: C₁₄H₁₂O₅

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 260.25

Ref: 5G-89481

Khellin

CAS: 82-02-0

Khellin is a natural product isolated from Bishop’s Weed, which is particularly abundant in the Mediterranean regions. Ancient Egyptians used the herb for the treatment of asthma and kidney stones, and since then has been used in a range of medicines. Nowadays Khellin is used in a treatment against arrhythmia and also as a photosensitizer in UVA Vitiligo treatment. Furanochromones like Khellin and Visnagin (FV42573) have also been found to have phytotoxic properties. For this reasons these natural compounds can be used as effective and environmentally benign herbicides.

Formula: C₁₄H₁₂O₅

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 260.24 g/mol

Ref: 3D-FK52456

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Molecular weight: 260.24

Ref: BE-RMCK018000

Khellin

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Molecular weight: 260.24

Ref: BE-RMT21406

Khellin

CAS: 82-02-0

4,9-Dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one

Formula: C₁₄H₁₂O₅

Purity: 95%

Molecular weight: 260.24

Ref: IN-DG15324

4,9-dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one

CAS: 82-02-0

Formula: C₁₄H₁₂O₅

Purity: ≥95%(GC)

Color and Shape: Solid

Molecular weight: 260.245

Ref: 10-F374699