CAS 82034-46-6
:Loteprednol etabonate
Description:
Loteprednol etabonate is a synthetic corticosteroid primarily used in ophthalmology for its anti-inflammatory properties. It is characterized by its ability to reduce inflammation and alleviate symptoms associated with allergic conjunctivitis and other ocular inflammatory conditions. The compound is a derivative of prednisolone, designed to minimize systemic absorption and enhance local efficacy when administered topically. Loteprednol etabonate exhibits a favorable safety profile, with a lower risk of intraocular pressure elevation compared to traditional corticosteroids, making it suitable for short-term use in treating eye conditions. Its mechanism of action involves the inhibition of inflammatory mediators, thereby reducing redness, swelling, and discomfort. The substance is typically formulated as an eye drop solution, allowing for direct application to the affected area. Overall, Loteprednol etabonate is valued for its targeted therapeutic effects and reduced side effects in the management of ocular inflammation.
Formula:C24H31ClO7
InChI:InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1
InChI key:InChIKey=DMKSVUSAATWOCU-HROMYWEYSA-N
SMILES:O(C(OCC)=O)[C@@]1(C(OCCl)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]
Synonyms:- Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (11β,17α)-
- CDDD 5604
- Chloromethyl (8xi,9xi,11beta,14xi,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
- chloromethyl (11beta,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate
- androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (8xi,9xi,11beta,14xi,17alpha)-
- Loteprednol etabonate
- P 5604
- HGP 1
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Found 14 products.
Loteprednol etabonate
CAS:Loteprednol etabonate (Lotemax) is an ophthalmic analog of the corticosteroid prednisolone with anti-inflammatory activity.Formula:C24H31ClO7Purity:99.19%Color and Shape:SolidMolecular weight:466.95(11b,17a)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-Androsta-1,4-diene-17-carboxylic acid chloromethyl ester
CAS:Formula:C24H31ClO7Purity:98%Color and Shape:SolidMolecular weight:466.9517Loteprednol etabonate
CAS:Formula:C24H31ClO7Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:466.95Loteprednol Etabonate-d5
CAS:Formula:C24H26D5ClO7Color and Shape:White To Off-White SolidMolecular weight:471.99Loteprednol Etabonate
CAS:Formula:C24H31ClO7Color and Shape:White To Off-White SolidMolecular weight:466.96Loteprednol Etabonate
CAS:Controlled ProductFormula:C24H31ClO7Color and Shape:NeatMolecular weight:466.95Loteprednol Etabonate
CAS:Formula:C24H31ClO7Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:466.96Loteprednol Etabonate
CAS:<p>Applications An ophthalmic corticosteroid. Used as an anti-inflammatory.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Formula:C24H31ClO7Color and Shape:WhiteMolecular weight:466.95Loteprednol etabonate
CAS:<p>Glucocorticoid receptor agonist</p>Formula:C24H31ClO7Purity:Min. 95%Color and Shape:White PowderMolecular weight:466.95 g/molLoteprednol etabonate - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C24H31ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:466.95 g/molLoteprednol Etabonate-d3
CAS:Controlled Product<p>Applications Labelled Loteprednol Etabonate, an ophthalmic corticosteroid. Used as an anti-inflammatory.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>Formula:C24H28D3ClO7Color and Shape:NeatMolecular weight:469.97
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