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CAS 82248-59-7

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Atomoxetine hydrochloride

Description:
Atomoxetine hydrochloride is a selective norepinephrine reuptake inhibitor primarily used in the treatment of attention deficit hyperactivity disorder (ADHD). It is characterized by its chemical formula, which includes a nitrogen-containing aromatic ring and a secondary amine, contributing to its pharmacological activity. The substance is typically presented as a white to off-white crystalline powder, soluble in water and various organic solvents. Atomoxetine hydrochloride exhibits a moderate to high bioavailability when administered orally, with a half-life that allows for once or twice daily dosing. Its mechanism of action involves the inhibition of norepinephrine transporters, leading to increased levels of norepinephrine in the synaptic cleft, which is believed to enhance attention and reduce impulsivity and hyperactivity in patients with ADHD. The compound is generally well-tolerated, though it may cause side effects such as gastrointestinal disturbances, fatigue, and changes in mood. As with any medication, it is essential to use Atomoxetine hydrochloride under the guidance of a healthcare professional to monitor for efficacy and potential adverse effects.
Formula:C17H22ClNO
InChI:InChI=1/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H
InChI key:InChIKey=LUCXVPAZUDVVBT-UNTBIKODSA-N
SMILES:[C@@H](OC1=C(C)C=CC=C1)(CCNC)C2=CC=CC=C2.Cl
Synonyms:
  • (3R)-N-methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine hydrochloride (1:1)
  • (R)-(-)-N-Methyl-3-[(2-methylphenyl)oxy]-3-phenyl-1-aminopropane hydrochloride
  • (R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine hydrochloride
  • (R)-N-Methyl-3-phenyl-3-(o-tolyloxy)propan-1-amine hydrochloride
  • (R)-N-Methyl-Gamma-(2-Methyl-Phenoxy)Benzenepropanamine Hydrochloride
  • (R)-Tomoxetine Hydrochloride
  • Atemoxetine hydrochloride
  • Atomoxetine HCl
  • Benzenepropanamine, N-methyl-γ-(2-methylphenoxy)-, hydrochloride (1:1), (γR)-
  • Benzenepropanamine, N-methyl-γ-(2-methylphenoxy)-, hydrochloride, (R)-
  • See more synonyms
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Found 19 products.