CAS 82410-32-0
:Ganciclovir
Description:
Ganciclovir is an antiviral medication primarily used to treat cytomegalovirus (CMV) infections, particularly in immunocompromised patients, such as those with HIV/AIDS or organ transplant recipients. It is a synthetic analog of guanosine and functions by inhibiting viral DNA synthesis. Ganciclovir is characterized by its white to off-white crystalline powder form, which is soluble in water and has a moderate molecular weight. The compound has a specific chemical structure that includes a hydroxymethyl group and a cyclic structure, contributing to its activity against CMV. Its mechanism of action involves selective phosphorylation by viral enzymes, leading to the termination of viral DNA chain elongation. Ganciclovir is typically administered intravenously or orally, and its use may be associated with side effects such as bone marrow suppression, which necessitates careful monitoring of blood counts during treatment. Overall, Ganciclovir is a crucial therapeutic agent in managing viral infections, particularly in vulnerable populations.
Formula:C9H13N5O4
InChI:InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChI key:InChIKey=IRSCQMHQWWYFCW-UHFFFAOYSA-N
SMILES:C(OC(CO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2
Synonyms:- 2'-Ndg
- 2'-Nor-2'-deoxyguanosine
- 2-Amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-6H-purin-6-one
- 2-Amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-3H-purin-6-one
- 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one
- 2-Amino-9-[[(1,3-dihydroxypropan-2-yl)oxy]methyl]-6,9-dihydro-3H-purin-6-one
- 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-
- 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)-methyl)guanine
- 9-(1,3-Dihydroxy-2-propoxymethyl)guanine
- Biolf 62
- Bw 759
- Bw 759U
- Bw-B 759U
- Denosine
- Dhpg
- Gancyclovir
- Ganguard
- Ganquard
- Gengxiluowei
- Hhemg
- Hydroxyacyclovir
- Nataclovir
- Natclovir
- Rs 21592
- Vitrasert
- See more synonyms
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Found 19 products.
Ganciclovir
CAS:Formula:C9H13N5O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:255.23Ganciclovir
CAS:<p>Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure</p>Formula:C9H13N504Color and Shape:White Off-White PowderMolecular weight:7178.651022-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one
CAS:Formula:C9H13N5O4Purity:98%Color and Shape:SolidMolecular weight:255.2306Ganciclovir
CAS:<p>Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus.</p>Formula:C9H13N5O4Purity:99.55% - 99.58%Color and Shape:White PowderMolecular weight:255.23Ganciclovir
CAS:Formula:C9H13N5O4Purity:≤ 0.5%Color and Shape:White to off-white powderMolecular weight:255.23Ganciclovir 100 µg/mL in Acetonitrile:Water
CAS:Formula:C9H13N5O4Color and Shape:Single SolutionMolecular weight:255.23Ganciclovir
CAS:<p>Ganciclovir</p>Formula:C9H13N5O4Purity:99.97% (Typical Value in Batch COA)Color and Shape: white solidMolecular weight:255.23g/molGanciclovir
CAS:Controlled Product<p>Applications Ganciclovir is a nucleoside analog structurally related to Acyclovir (A192400). Ganciclovir is an antiviral.<br>References Halloran, P.J. and Fenton, R.G.: Cancer Res., 58, 3855 (1998), Rubsam, L.Z., et al.: Cancer Res., 59, 669 (1999), Yamasaki, H., et al.: C.R. Acad. Sci. III, 322, 151 (1999)<br></p>Formula:C9H13N5O4Color and Shape:White To Off-WhiteMolecular weight:255.23Ganciclovir - Bio-X ™
CAS:<p>Ganciclovir is an acyclovir analog that is used in the treatment of cytomegalovirus and herpetic keratitis of the eye. This drug is a DNA polymerase inhibitor and exhibits its anti-viral properties by inhibiting viral replication.</p>Formula:C9H13N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:255.23 g/molGanciclovir
CAS:<p>Ganciclovir is an antiviral drug that inhibits viral DNA synthesis, leading to cell death. It is used for the treatment of cytomegalovirus retinitis, herpes zoster (shingles), and condyloma acuminata. Ganciclovir is also used as a preventative measure against opportunistic infection with HIV or CMV in people with AIDS. It is given intravitreally, by injection into the eye, with human immunoglobulin G (IgG) to prevent CMV in persons who have been exposed to it. The combination therapy group includes ganciclovir and acyclovir. Drug interactions can occur when ganciclovir is administered intravenously with heparin-containing solutions or drugs containing polymyxin B sulfate or colistimethate sodium. Ganciclovir has shown antiviral resistance in SCC cells and may lead to neuronal death when used on rats in</p>Formula:C9H13N5O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:255.23 g/mol2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1H-purin-6(9H)-one
CAS:Formula:C9H13N5O4Purity:95.0%Color and Shape:SolidMolecular weight:255.234Ganciclovir, Antibiotic for Culture Media Use Only
CAS:<p>Ganciclovir is an antiviral agent specifically designed for culture media use. It is a synthetic analogue of 2'-deoxy-guanosine, derived from nucleoside compounds, and operates primarily by inhibiting the replication of viral DNA. Its mode of action involves selective phosphorylation by viral kinases, which converts it into ganciclovir triphosphate, a potent inhibitor of viral DNA polymerase, ultimately preventing viral DNA synthesis.</p>Formula:C9H13N5O4Purity:Min. 98.0 Area-%Molecular weight:255.23 g/mol
![2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA008JZU.jpg&w=3840&q=75)
