CAS 82586-52-5

Moexipril hydrochloride

Description:

Moexipril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension. It is a prodrug that is converted in the body to its active form, moexiprilat, which exerts its pharmacological effects by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. The chemical formula for moexipril hydrochloride includes a complex structure featuring a proline derivative, which contributes to its efficacy and specificity. It is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels, among others. As with other ACE inhibitors, it is contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy and should be used cautiously in individuals with renal impairment. Overall, moexipril hydrochloride is an important therapeutic agent in managing cardiovascular health.

Formula: C₂₇H₃₄N₂O₇·ClH

InChI: InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

InChI key: InChIKey=JXRAXHBVZQZSIC-JKVLGAQCSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2CC=3C(C[C@H]2C(O)=O)=CC(OC)=C(OC)C3.Cl

Synonyms:

• (3S)-2-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisochinolin-3-carbons?urehydrochlorid
• (3S)-2-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride (1:1)
• (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)
• (3S-(2(R*(R*)),3R*))-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-3-isoquinolinecarboxylic acid monohydrochloride
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, hydrochloride (1:1)
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1), (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
• 3-isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, monohydrochloride
• Ci 925
• Moexipril HCl
• Primox
• Rs 10085-197
• Spm 925
• Univasc

Moexipril Hydrochloride

CAS: 82586-52-5

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₂₇H₃₄N₂O₇·HCl

Color and Shape: Powder

Molecular weight: 498.2366

Ref: 45-1445426

Moexipril-d5 HCl

CAS: 1356929-49-1, 82586-52-5

Formula: C₂₇H₂₉D₅N₂O₇·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 503.61 36.46

Ref: 4Z-M-312

Moexipril hydrochloride

CAS: 82586-52-5

Formula: C₂₇H₃₅N₂O₇Cl

Purity: ≥ 98.0%

Color and Shape: Conflicting attributes defined

Molecular weight: 535.03

Ref: 7W-GP1850

Moexipril HCl

CAS: 82586-52-5

Formula: C₂₇H₃₄N₂O₇·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 498.58 36.46

Ref: 4Z-M-311

Moexipril hydrochloride

CAS: 82586-52-5

Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of

Formula: C₂₇H₃₄N₂O₇·HCl

Purity: 97.8%

Color and Shape: A Fine White To Off-White Powder

Molecular weight: 535.03

Ref: TM-T6595

Moexipril Hydrochloride

CAS: 82586-52-5

Formula: C₂₇H₃₄N₂O₇HCl

Molecular weight: 498.6 : 36.46

Ref: ST-EA-CP-M62002

Moexipril Hydrochloride

Controlled Product

CAS: 82586-52-5

Applications Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril.
References Edling, O., et al.: J. Pharmacol. Exp. Ther., 275, 854 (1995), White, W.B., et al.: J. Hum. Hypertens., 8, 917 (1994), Stimpel, M., et al.: Cardiology 87, 313 (1996)

Formula: C₂₇H₃₄N₂O₇·ClH

Color and Shape: Neat

Molecular weight: 535.03

Ref: TR-M485350

Moexipril HCl

CAS: 82586-52-5

Inhibitor of angiotensin converting enzyme

Formula: C₂₇H₃₅ClN₂O₇

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 535.03 g/mol

Ref: 3D-FM26040

Moexipril HCl - Bio-X ™

CAS: 82586-52-5

Moexipril is an angiotensin converting enzyme inhibitor that is used for the treatment of hypertension. This drug is a prodrug for moexiprilat and works by relaxing the blood vessels causing them to widen and lowering blood pressure. Moexipril has been shown to be effective in treating metabolic disorders such as congestive heart failure.

Formula: C₂₇H₃₄N₂O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 498.57 g/mol

Ref: 3D-BM164604

Moexipril hydrochloride

CAS: 82586-52-5

Ref: BE-RMCM228001