CAS 82640-04-8: Raloxifene hydrochloride

Description: Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of osteoporosis in postmenopausal women. It exhibits estrogenic activity on bone tissue, helping to maintain bone density, while acting as an antagonist in breast and uterine tissues, thus reducing the risk of estrogen-related cancers. The compound is characterized by its ability to bind to estrogen receptors, influencing gene expression and cellular activity. Raloxifene hydrochloride is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life. Common side effects may include hot flashes, leg cramps, and an increased risk of thromboembolic events. The substance is also investigated for its potential cardiovascular benefits and its role in reducing the risk of invasive breast cancer. As with any medication, it is essential to consider contraindications and interactions with other drugs when prescribing or using Raloxifene hydrochloride.

Formula: C₂₈H₂₇NO₄S·ClH

InChI: InChI=1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H

InChI key: InChIKey=BKXVVCILCIUCLG-UHFFFAOYSA-N

SMILES: Cl.O=C(C1=CC=C(OCCN2CCCCC2)C=C1)C3=C(SC4=CC(O)=CC=C43)C=5C=CC(O)=CC5

Synonyms:

• 2-(4-Hydroxyphenyl)-3-[4-[2-(piperidin-1-yl)ethoxy]benzoyl]-1-benzothiophen-6-ol hydrochloride
• 6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride
• Bonebay
• Bontact
• Evista
• Fiona
• Keoxifene hydrochloride
• Ly 156758
• Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride
• Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-, hydrochloride (1:1)
• Optruma
• Ralista
• Ralofen
• Raloxifene HCl
• Raloxifene hydrochloride [USAN]
• Reloxafine
• Unii-4F86W47Br6
• [6-Hydroxy-2-(4-Hydroxyphenyl)-1-Benzothiophen-3-Yl]{4-[2-(Piperidin-1-Yl)Ethoxy]Phenyl}Methanone Hydrochloride (1:1)
• [6-Hydroxy-2-(4-Hydroxyphenyl)-2,3-Dihydro-1-Benzothiophen-3-Yl][4-(2-Piperidin-1-Ylethoxy)Phenyl]Methanone
• Raloxifene hydrochloride

Raloxifene Hydrochloride

CAS: 82640-04-884449-90-1

• Formula: C₂₈H₂₇NO₄S·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: Light yellow to Yellow to Green powder to crystal
• Molecular weight: 510.05

Raloxifene for peak identification CRS

CAS: 82640-04-8

• Formula: C₂₈H₂₈ClNO₄S
• Molecular weight: 510.0442

Raloxifene hydrochloride CRS

CAS: 82640-04-8

• Formula: C₂₈H₂₈ClNO₄S
• Color and Shape: White. Light Yellow. Powder.
• Molecular weight: 510.0442

Raloxifene Hydrochloride

CAS: 82640-04-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₂₈H₂₇NO₄S·HCl
• Color and Shape: Off-White Light Yellow Yellow Green Powder
• Molecular weight: 510.04

Methanone, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1)

CAS: 82640-04-8

• Formula: C₂₈H₂₈ClNO₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 510.0442

Raloxifene hydrochloride

CAS: 82640-04-8

Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.

• Formula: C₂₈H₂₈ClNO₄S
• Purity: 98% - 99.81%
• Color and Shape: Light Yellow Solid
• Molecular weight: 510.044

Raloxifene hydrochloride

CAS: 82640-04-8

• Formula: C₂₈H₂₇NO₄S·HCl
• Purity: ≥ 99.0%
• Color and Shape: Light yellow crystalline powder
• Molecular weight: 510.04

Raloxifene HCl

CAS: 82640-04-8

• Formula: C₂₈H₂₇NO₄S·HCl
• Color and Shape: Yellow Solid
• Molecular weight: 473.59 36.46

Raloxifene Hydrochloride

CAS: 82640-04-8

• Formula: C₂₈H₂₇NO₄S·ClH
• Color and Shape: Neat
• Molecular weight: 510.04

Raloxifene Hydrochloride

CAS: 82640-04-8

Applications A nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.Insoluble in water. Not a dangerous good …

• Formula: C₂₈H₂₇NO₄S·ClH
• Color and Shape: Light Yellow Solid
• Molecular weight: 510.04

Raloxifene Hydrochloride

CAS: 82640-04-8

• Formula: C₂₈H₂₇NO₄SHCl
• Molecular weight: 473.59 : 36.46

Raloxifene HCl - Bio-X ™

CAS: 82640-04-8

Raloxifene is an estrogen receptor modulator that is used in the prevention and treatment of …

• Formula: C₂₈H₂₇NO₄S•HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 510.04 g/mol

Raloxifene hydrochloride

CAS: 82640-04-8

Estrogen receptor modulator

• Formula: C₂₈H₂₈ClNO₄S
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 510.04 g/mol

Raloxifene-d10 Hydrochloride

CAS: 82640-04-8

Applications Raloxifene-d10 Hydrochloride, is the labeled analogue of Raloxifene (R100000), a nonsteroidal, selective estrogen receptor …

• Formula: C₂₈H₁₈D₁₀ClNO₄S
• Color and Shape: Neat
• Molecular weight: 520.11