CAS 827044-38-2

L-Lysine,N-(2-aminobenzoyl)glycyl-L-isoleucyl-L-valyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-(9CI)

Description:

L-Lysine, N-(2-aminobenzoyl)glycyl-L-isoleucyl-L-valyl-L-arginyl-L-alanyl-N6-(2,4-dinitrophenyl)-(9CI) is a complex peptide derivative characterized by its multi-residue structure, which includes amino acids such as lysine, isoleucine, valine, arginine, and alanine, along with a dinitrophenyl group. This compound is typically used in biochemical research and may serve as a model for studying peptide interactions, protein synthesis, or as a potential therapeutic agent. The presence of the dinitrophenyl group suggests that it may be involved in specific binding interactions or serve as a marker for detection in various assays. The compound's solubility, stability, and reactivity can vary depending on the pH and solvent conditions, which are critical for its application in laboratory settings. Additionally, its molecular weight and structural properties influence its biological activity and potential uses in drug development or as a biochemical probe. As with any chemical substance, proper handling and safety protocols should be observed due to potential toxicity associated with certain functional groups.

Formula: C₄₁H₆₁N₁₃O₁₂

Synonyms:

• Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-Oh

Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH

CAS: 827044-38-2

Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 µM, kcat = 43 s⁻¹, kcat/Km = 7288 mM⁻¹s⁻¹). The kcat/Km values for cathepsin K, L, V, X, and cruzain were 133.3, 100, 32, 17, and 75 mM⁻¹s⁻¹, respectively.

Formula: C₄₁H₆₁N₁₃O₁₂

Purity: 96.7%

Color and Shape: Yellow Lyophilisate

Molecular weight: 928.02

Ref: 01-4049308

Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH

CAS: 827044-38-2

Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH is a protease inhibitor that has been shown to inhibit the activity of proteinases, such as collagenase, elastase and cathepsin G. It also inhibits the growth of leishmania parasites. Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH was also found to be potent in inhibiting the proteolytic activity of cancer cells. The inhibition is due to its ability to form tight complexes with the active site of enzymes such as trypsin and chymotrypsin. This compound has potential for use in animal experiments and in vitro assays.

Formula: C₄₁H₆₁N₁₃O₁₂

Purity: Min. 95%

Molecular weight: 928 g/mol

Ref: 3D-FA110982