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CAS 82857-69-0

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Benzylacyclouridine

Description:
Benzylacyclouridine is a synthetic nucleoside analog that has garnered interest in the field of medicinal chemistry, particularly for its potential antiviral and anticancer properties. It is characterized by a unique structure that combines a benzyl group with an acyclouridine backbone, which contributes to its biological activity. The compound exhibits a modified sugar moiety, which enhances its stability and bioavailability compared to natural nucleosides. Benzylacyclouridine has been studied for its ability to inhibit viral replication and may interfere with nucleic acid synthesis in various pathogens. Its mechanism of action often involves the incorporation into viral RNA or DNA, leading to termination of nucleic acid chain elongation. Additionally, the compound's lipophilic nature, due to the benzyl group, may facilitate its cellular uptake. Research continues to explore its therapeutic potential, optimal dosing, and side effects, making it a subject of interest in drug development and pharmacology. Overall, Benzylacyclouridine represents a significant advancement in the design of nucleoside analogs for therapeutic applications.
Formula:C14H16N2O4
InChI:InChI=1S/C14H16N2O4/c17-6-7-20-10-16-9-12(13(18)15-14(16)19)8-11-4-2-1-3-5-11/h1-5,9,17H,6-8,10H2,(H,15,18,19)
InChI key:InChIKey=SPJAGILXQBHHSZ-UHFFFAOYSA-N
SMILES:C(C1=CN(COCCO)C(=O)NC1=O)C2=CC=CC=C2
Synonyms:
  • 1-[(2-Hydroxyethoxy)methyl]-5-(phenylmethyl)-2,4(1H,3H)-pyrimidinedione
  • 2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(phenylmethyl)-
  • 5-Benzyl-1-(2-hydroxyethoxymethyl)uracil
  • 5-Benzylacyclouridine
  • Benzylacyclouridine
  • BAU
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