CAS 83-73-8

5,7-Diiodo-8-hydroxyquinoline

Description:

5,7-Diiodo-8-hydroxyquinoline is an organic compound characterized by its quinoline structure, which features a hydroxyl group and two iodine substituents at the 5 and 7 positions. This compound is known for its potential applications in various fields, including pharmaceuticals and materials science. It exhibits properties such as being a chelating agent, which allows it to form stable complexes with metal ions, making it useful in analytical chemistry and as a potential therapeutic agent. The presence of iodine atoms enhances its reactivity and can influence its biological activity. Additionally, the hydroxyl group contributes to its solubility in polar solvents and can participate in hydrogen bonding. 5,7-Diiodo-8-hydroxyquinoline is also noted for its fluorescent properties, which can be advantageous in imaging and sensing applications. However, handling this compound requires caution due to the toxicity associated with iodine-containing compounds and the need for proper safety protocols in laboratory settings.

Formula: C₉H₅I₂NO

InChI: InChI=1S/C9H5I2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

InChI key: InChIKey=UXZFQZANDVDGMM-UHFFFAOYSA-N

SMILES: OC=1C2=C(C(I)=CC1I)C=CC=N2

Synonyms:

• 5,7-Diiodo-8-quinolinol
• 5,7-Diiodooxine
• 5,7-Diiodoquinolin-8-Ol
• 8-Hydroxy-5,7-diiodoquinoline
• 8-Quinolinol, 5,7-diiodo-
• Di-Quinol
• Diamoebin
• Diiodohydroxyquin
• Diiodohydroxyquinoline
• Diiodoquin
• Diiodoquinol
• Dinoleine
• Diodohydroxyquin
• Diodoquin
• Diodoxylin
• Direxiode
• Disoquin
• Dyodin
• Embequin
• Enterodiamoebin
• Enterosept
• Floraquin
• Iodoquin
• Iodoquinol
• Ioquin
• Lanodoxin
• Moebiquin
• NSC 74939
• NSC 8704
• Quinadome
• Rafamebin
• Searlequin
• Searlewuin
• Sebaquin
• Ss 578
• Stanquinate
• Yodoxin

Iodoquinol

CAS: 83-73-8

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₉H₅I₂NO

Color and Shape: Light Brown Yellow Powder

Molecular weight: 396.84606

Ref: 45-1344509

5,7-diiodoquinolin-8-ol

CAS: 83-73-8

Formula: C₉H₅I₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 396.9510

Ref: IN-DA00346C

Diiodohydroxyquinoline

CAS: 83-73-8

Diiodohydroxyquinoline (Iodoquinol), a topical therapeutic agent, has satisfactory antibacterial properties.

Formula: C₉H₅I₂NO

Purity: 97.74%

Color and Shape: Solid

Molecular weight: 396.95

Ref: TM-T0513

Diiodohydroxyquinoline

CAS: 83-73-8

Diiodohydroxyquinoline

Formula: C₉H₅I₂NO

Purity: ≥95%

Molecular weight: 396.95

Ref: 54-BUP19778

DIIodohydroxyquinoline

CAS: 83-73-8

DIIodohydroxyquinoline

Formula: C₉H₅I₂NO

Purity: 98%

Molecular weight: 396.95

Ref: 54-OR1029777

Iodoquinol

CAS: 83-73-8

Formula: C₉H₅I₂NO

Molecular weight: 396.95

Ref: 7W-GP7897

Clioquinol EP Impurity C

CAS: 83-73-8

Formula: C₉H₅I₂NO

Color and Shape: Pale Yellow Solid

Molecular weight: 396.95

Ref: 4Z-C-803

Iodoquinol (5,7-Diiodoquinolin-8-ol)

CAS: 83-73-8

Color and Shape: Neat

Ref: 61-FOR0312.03

5,7-Diiodoquinolin-8-ol

CAS: 83-73-8

Color and Shape: Light Yellow To Beige

Ref: 86-MM0312.03

Iodoquinol

CAS: 83-73-8

Applications Antiamebic.
References Lawrence, S., et al.: J. Biol. Chem., 284, 35807 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₉H₅I₂NO

Color and Shape: Neat

Molecular weight: 396.95

Ref: TR-I728400

Iodoquinol

CAS: 83-73-8

Iodoquinol is a quinoline derivative that has been shown to have antifungal properties in vitro. It is used to treat bowel disease and infectious diseases, such as malaria and tuberculosis. Iodoquinol has also been shown to reduce the incidence of autoimmune diseases by inhibiting the production of pro-inflammatory cytokines. The mechanism of action for this drug is not well understood, but it is believed that it reacts with DNA and may inhibit the synthesis of proteins. It has also been shown to cause genotoxic effects in a model system by binding covalently to DNA, as well as benzalkonium chloride

Formula: C₉H₅I₂NO

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 396.95 g/mol

Ref: 3D-FI24630

5,7-Diiodo-8-Quinolinol (Diiodohydroxyquinoline, Iodoquinol) ExiPlus, 96.5%

CAS: 83-73-8

Formula: C₉H₅I₂NO

Purity: Min.96.5%

Color and Shape: Off white to Yellow to Greenish tan, Powder or Crystal

Molecular weight: 396.95

Ref: SR-19022

5,7-Diiodo-8-hydroxyquinoline

CAS: 83-73-8

Formula: C₉H₅I₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 396.954

Ref: 10-F131600

Clioquinol EP Impurity C

CAS: 83-73-8

Formula: C₉H₅I₂NO

Molecular weight: 396.95

Ref: ST-EA-CP-C41003

Iodoquinol

CAS: 83-73-8

Iodoquinol is a quinolone antibiotic that is used as an anti-infective agent. It has been approved by the FDA for the treatment of bacterial vaginosis, and it has also been shown to be effective against other conditions such as inflammatory diseases and autoimmune diseases. Iodoquinol has been shown to have genotoxic effects by binding to DNA in human cells and causing damage. This drug can act as a free radical scavenger and suppress inflammation, which may be due to its ability to inhibit fatty acid synthesis in the body.

Formula: C₉H₅I₂NO

Purity: Min. 95%

Color and Shape: Light (Or Pale) Yellow To Yellow Brown Solid

Molecular weight: 396.95 g/mol

Ref: 3D-FI172023