CAS 83199-32-0

RP-TTP-ALPHA-S/RP-DTTP-ALPHA-S SODIUM SALT

Formula: C₁₀H₁₃N₂Na₄O₁₃P₃S

InChI: InChI=1S/C10H17N2O13P3S/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(23-8)4-22-28(21,29)25-27(19,20)24-26(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,29)(H,11,14,15)(H2,16,17,18)/t6-,7+,8+,28?/m0/s1

InChI key: PXHHTOSRELKWOE-MXWQNOQOSA-N

SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)(O)OP(=O)(O)OP(=O)(O)O)O

Synonyms:

• thymidine-5’-o-(1-thiotriphosphate),sp-isomer(sp-ttp-alpha-s),sodiumsalt
• THYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER/2'-DEOXYTHYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT
• dTTPαS (Sp isomer) 100mM Sodium Solution
• RP-TTP-ALPHA-S/RP-DTTP-ALPHA-S SODIUM SALT
• THYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), RP-ISOMER/2'-DEOXYTHYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), RP-ISOMER SODIUM SALT
• SP-TTP-ALPHA-S/SP-DTTP-ALPHA-S SODIUM SALT
• Sp-TTP-α-S
• Thymidine, 5-P-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), (S)-

Sp-TTPαS

CAS: 83199-32-0

Sp-TTPαS is a competitive inhibitor of the catalytic activity of sterile alpha motif and HD domain containing protein 1 (SAMHD1). It competitively inhibits TTP hydrolysis, with a Ki value of 46 µM.

Formula: C₁₀H₁₇N₂O₁₃P₃S

Color and Shape: Solid

Molecular weight: 498.23

Ref: TM-T88752