CAS 83435-58-9

N-ALPHA-tert-Butoxycarbonyl-D-prolinol

Description:

N-Alpha-tert-Butoxycarbonyl-D-prolinol, with the CAS number 83435-58-9, is a chemical compound commonly used in organic synthesis, particularly in the field of peptide chemistry. It features a tert-butoxycarbonyl (Boc) protecting group, which is often employed to protect amines during chemical reactions. The presence of the D-prolinol moiety indicates that it is a derivative of proline, an amino acid that plays a crucial role in protein structure and function. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide (DMSO). Its stability under various conditions makes it a valuable intermediate in the synthesis of more complex molecules. Additionally, the Boc group can be easily removed under acidic conditions, allowing for the subsequent functionalization of the prolinol moiety. Overall, N-Alpha-tert-Butoxycarbonyl-D-prolinol is an important reagent in the development of pharmaceuticals and biologically active compounds.

Formula: C₁₀H₁₉NO₃

InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(11)7-12/h8,12H,4-7H2,1-3H3/t8-/m1/s1

InChI key: BFFLLBPMZCIGRM-MRVPVSSYSA-N

SMILES: CC(C)(C)OC(=O)N1CCC[C@@H]1CO

Synonyms:

• BOC-D-Prolinol
• N-Boc-D-prolinol
• Boc-D-Pro-ol
• N-(tert-Butoxycarbonyl)-D-prolinol
• (R)-(+)-1-tert-Butoxycarbonyl-2-pyrrolidinemethanol

N-(tert-Butoxycarbonyl)-D-prolinol

CAS: 83435-58-9

Formula: C₁₀H₁₉NO₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 201.27

Ref: 3B-B3076

N-Boc-D-prolinol

CAS: 83435-58-9

Formula: C₁₀H₁₉NO₃

Molecular weight: 201.27

Ref: 7W-GM1069

N-BOC-D-Prolinol

CAS: 83435-58-9

N-BOC-D-Prolinol

Formula: C₁₀H₁₉NO₃

Purity: >98%

Color and Shape: Solid

Molecular weight: 201.26275

Ref: 54-OR315048

N-Boc-D-prolinol

CAS: 83435-58-9

Formula: C₁₀H₁₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 201.2628

Ref: IN-DA003C74

Boc-D-Prolinol

CAS: 83435-58-9

Boc-D-Prolinol

Formula: C₁₀H₁₉NO₃

Purity: 97%

Molecular weight: 201.26

Ref: IN-DG220113

1-Boc-D-Prolinol

CAS: 83435-58-9

Formula: C₁₀H₁₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 201.266

Ref: 10-F036673

N-(tert-Butoxycarbonyl)-D-prolinol

Controlled Product

CAS: 83435-58-9

Applications N-(tert-Butoxycarbonyl)-D-prolinol is used to prepare (azetidinyl)methoxy]pyridines and 2-(aryloxymethyl) azacyclic analogs with therapeutic potetials for the treatment of central nervous system (CNS) disorders.
References Abreo, M., et al.: J. Med. Chem., 39, 817 (1996); Elliott, R., et al.: Bioorg. Med. Lett., 6, 2283 (1996)

Formula: C₁₀H₁₉NO₃

Color and Shape: Neat

Molecular weight: 201.26

Ref: TR-B689475