CAS 83643-88-3

S-AMPA

Description:

S-AMPA, or (S)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid, is a synthetic compound that acts as a selective agonist for the AMPA subtype of glutamate receptors in the central nervous system. It is characterized by its ability to enhance synaptic transmission and is often used in neuroscience research to study excitatory neurotransmission and synaptic plasticity. S-AMPA is known for its high potency and selectivity, making it a valuable tool in pharmacological studies. The compound is typically administered in experimental settings to investigate its effects on neuronal activity, learning, and memory processes. Its chemical structure includes an isoxazole ring, which is integral to its function as a receptor agonist. Additionally, S-AMPA is soluble in water and exhibits stability under physiological conditions, which is crucial for its application in biological experiments. As with many research chemicals, safety and handling precautions are essential due to potential neuroactive effects.

Formula: C₇H₁₀N₂O₄

InChI: InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1

InChI key: InChIKey=UUDAMDVQRQNNHZ-YFKPBYRVSA-N

SMILES: C([C@@H](C(O)=O)N)C=1C(=O)NOC1C

Synonyms:

• (2S)-2-Amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid
• (2S)-2-Amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
• (2S)-2-Amino-3-(5-methyl-3-oxo-4-isoxazolyl)propanoic acid
• (S)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
• (αS)-α-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
• 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (S)-
• 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (αS)-
• <span class="text-smallcaps">L</span>-AMPA
• S-Ampa
• L-AMPA

(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

CAS: 83643-88-3

Formula: C₇H₁₀N₂O₄

Purity: 99.0%

Color and Shape: Solid

Molecular weight: 186.1653

Ref: IN-DA003CMU

(S)-AMPA

CAS: 83643-88-3

(S)-AMPA

Purity: 98%

Ref: 54-OR1037181

(S)-AMPA

CAS: 83643-88-3

Formula: C₇H₁₀N₂O₄

Purity: (HPLC) ≥ 99.0%

Color and Shape: White solid

Molecular weight: 186.16

Ref: 7W-GL3824

(S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

CAS: 83643-88-3

M01254 - (S)-alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Formula: C₇H₁₀N₂O₄

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 186.167

Ref: 10-M01254

(S)-AMPA

Controlled Product

CAS: 83643-88-3

Formula: C₇H₁₀N₂O₄

Color and Shape: Neat

Molecular weight: 186.165

Ref: TR-A634290

(S)-AMPA

CAS: 83643-88-3

(S)-AMPA is a neurotransmitter that functions as an excitatory amino acid. (S)-AMPA is synthesized from glutamate by the enzyme glutamate decarboxylase and binds to the AMPA receptor, which is a type of ionotropic glutamate receptor. These receptors are found at synapses and are responsible for synaptic plasticity. (S)-AMPA modulates neuronal activity by binding to these receptors, altering the flow of ions across the cell membrane. It has been shown that (S)-AMPA can induce synaptic plasticity and long-term potentiation in the hippocampus in rats.

Formula: C₇H₁₀N₂O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 186.17 g/mol

Ref: 3D-IDA64388

(S)-AMPA

CAS: 83643-88-3

(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.

Formula: C₇H₁₀N₂O₄

Color and Shape: Solid

Molecular weight: 186.17

Ref: TM-T21271