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CAS 83643-88-3

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S-AMPA

Description:
S-AMPA, or (S)-α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid, is a synthetic compound that acts as a selective agonist for the AMPA subtype of glutamate receptors in the central nervous system. It is characterized by its ability to enhance synaptic transmission and is often used in neuroscience research to study excitatory neurotransmission and synaptic plasticity. S-AMPA is known for its high potency and selectivity, making it a valuable tool in pharmacological studies. The compound is typically administered in experimental settings to investigate its effects on neuronal activity, learning, and memory processes. Its chemical structure includes an isoxazole ring, which is integral to its function as a receptor agonist. Additionally, S-AMPA is soluble in water and exhibits stability under physiological conditions, which is crucial for its application in biological experiments. As with many research chemicals, safety and handling precautions are essential due to potential neuroactive effects.
Formula:C7H10N2O4
InChI:InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1
InChI key:InChIKey=UUDAMDVQRQNNHZ-YFKPBYRVSA-N
SMILES:C([C@@H](C(O)=O)N)C=1C(=O)NOC1C
Synonyms:
  • (2S)-2-Amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid
  • (2S)-2-Amino-3-(5-methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)propanoic acid
  • (2S)-2-Amino-3-(5-methyl-3-oxo-4-isoxazolyl)propanoic acid
  • (S)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
  • (αS)-α-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid
  • 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (S)-
  • 4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, (αS)-
  • <span class="text-smallcaps">L</span>-AMPA
  • S-Ampa
  • L-AMPA
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