CAS 83846-83-7

Ketanserin tartrate

Description:

Ketanserin tartrate is a pharmaceutical compound primarily used as an antihypertensive agent and for the treatment of certain psychiatric conditions. It is a selective antagonist of the serotonin 5-HT2A receptor and also exhibits some alpha-1 adrenergic receptor blocking activity. This dual action contributes to its effectiveness in managing blood pressure and improving mood disorders. Ketanserin tartrate is typically administered in its tartrate salt form, which enhances its solubility and bioavailability. The compound is characterized by its relatively low toxicity profile, making it suitable for long-term use in patients. Its pharmacokinetics involve oral administration, with a moderate half-life that allows for once or twice daily dosing. Common side effects may include dizziness, fatigue, and gastrointestinal disturbances, reflecting its influence on neurotransmitter systems. Overall, Ketanserin tartrate is recognized for its therapeutic benefits in cardiovascular and psychiatric applications, although its use may be limited by the availability of newer agents with improved efficacy and safety profiles.

Formula: C₂₆H₂₈FN₃O₉

InChI: InChI=1/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2+

InChI key: InChIKey=KMTLTEVOQLMYRS-LREBCSMRSA-N

SMILES: O=C1C=2C(NC(=O)N1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)=CC=CC2.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O

Synonyms:

• 2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
• 2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1)
• Ketanserine tartrate
• Kjk 945
• Perketan
• R 49945
• Serepress
• Sufrexal
• Ketanserin tartrate
• 3-[2-[4-(4-fluorobenzoyl)piperidino]ethyl]quinazoline-2,4(1H,3H)-dione [R-(R*,R*)]-tartrate
• KETANSERIN TARTRATE (R 41468) (SELECTIVE 5-HT2/5-HT1C SEROTONI
• r-(r*,r*))-2,3-dihydroxybutanedioate(1:1)
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,4[1H,3H]-QUINAZOLINEDIONE TARTRATE
• 3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4-(1H,3H)-quinazolinedione tartrate
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE
• 3-(2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL)-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE SALT
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE
• R 41468
• KETANSERIN TARTRATE SALT
• 3-(2-(4-(p-fluorobenzoyl)-1-piperidinyl)ethyl)-2,4(1h,3h)-quinazolinedionel
• 3-[2-(4-FLUOROBENZOYL)-1-PIPERDINYL]-ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE
• 4(1h,3h)-quinazolinedione,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-(
• R 41468 (+)-tartrate salt, 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt
• R 41468 TARTRATE SALT

Ketanserin tartrate, 98+%

CAS: 83846-83-7

Selective 5-HT2A serotonin receptor antagonist

Formula: C₂₂H₂₂FN₃O₃·C₄H₆O₆

Purity: 98+%

Color and Shape: powder, White to off-white

Molecular weight: 545.52

Ref: 02-J62798

3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate

CAS: 83846-83-7

Formula: C₂₆H₂₈FN₃O₉

Purity: 97%

Color and Shape: Solid

Molecular weight: 545.5136

Ref: IN-DA00IDBX

Ketanserin Tartrate

CAS: 83846-83-7

Ketanserin Tartrate

Purity: 97%

Molecular weight: 545.51g/mol

Ref: 54-PC109131

Ketanserin tartrate

CAS: 83846-83-7

Ketanserin tartrate

Purity: ≥98%

Molecular weight: 545.51g/mol

Ref: 54-BUP11748

Ketanserin (+)-tartrate salt

CAS: 83846-83-7

Formula: C₂₂H₂₂FN₃O₃·C₄H₆O₆

Molecular weight: 545.52

Ref: 7W-GL9943

Ketanserin tartrate

CAS: 83846-83-7

Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist for the study of systemic sclerosis.

Formula: C₂₆H₂₈FN₃O₉

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 545.51

Ref: TM-T1066L

Ketanserin Tartrate

Controlled Product

CAS: 83846-83-7

Applications Ketanserin Tartrate is used in nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis for preventing a variety of diseases ranging from cancer to ischemic injury.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gohil, V. M., et al.: Nat. Biotechnol, 28, 249 (2010)

Formula: C₂₂H₂₂FN₃O₃·C₄H₆O₆

Color and Shape: Off-White

Molecular weight: 545.51

Ref: TR-K165453

Ketanserin tartrate - Bio-X ™

CAS: 83846-83-7

Ketanserin is a 5-HT2A serotonin receptor antagonist that is used for the treatment of hypertension. This drug is also used in research to study the serotonergic system. Ketanserin has been found to also block the vesicular monoamine transporter 2.

Formula: C₂₂H₂₂FN₃O₃•C₄H₆O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 545.51 g/mol

Ref: 3D-BK164598

Ketanserin tartrate

CAS: 83846-83-7

5-HT2A serotonin receptor antagonist

Formula: C₂₆H₂₈FN₃O₉

Purity: Min. 99.0 Area-%

Molecular weight: 545.51 g/mol

Ref: 3D-J-034664

Ketanserin tartrate

CAS: 83846-83-7

5-HT2A serotonin receptor antagonist

Formula: C₂₂H₂₂FN₃O₃•C₄H₆O₆

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 545.51 g/mol

Ref: 3D-FK31491

Ketanserin Tartrate

CAS: 83846-83-7

M02041 - Ketanserin Tartrate

Formula: C₂₆H₂₈FN₃O₉

Purity: 97%

Color and Shape: Solid

Molecular weight: 545.52

Ref: 10-M02041