
CAS 83864-69-1
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Angeloylgomisin O
CAS:Angeloylgomisin O is a biphenylocyclooctadiene-type lignan isolated from Schisandra rubriflora. Angeloylgomisin O exhibits anti-inflammatory activity.Formula:C28H34O8Purity:99.68%Color and Shape:SolidMolecular weight:498.5648Angeloylgomisin O
CAS:Controlled ProductAngeloylgomisin O is a hypoglycemic compound that has been found to have anti-inflammatory effects. It is derived from the oleanonic acid, which can be found in many fruits and vegetables, such as the tomato and strawberry. Angeloylgomisin O was shown to inhibit signal pathways of inflammatory diseases, such as kidney fibrosis. It has also been shown to reduce dry weight in diabetic patients. Angeloylgomisin O is a specific inhibitor of protein kinase C delta (PKCδ), which is involved in the progression of kidney fibrosis in diabetes. The compound also inhibits the activity of fructus and mcf-7, two enzymes that are responsible for producing proinflammatory cytokines and chemokines, respectively. Angeloylgomisin O has been shown to have a molecular docking score of -1.00 with PKCδ and -0.94 with p38 MAPK.
Purity:Min. 95%







