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CAS 83881-51-0

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Cetirizine

Description:
Cetirizine is an antihistamine commonly used to alleviate allergy symptoms such as sneezing, runny nose, and itchy eyes. It is classified as a second-generation antihistamine, which means it is less likely to cause sedation compared to first-generation antihistamines. Cetirizine works by selectively inhibiting the H1 histamine receptor, thereby reducing the effects of histamine in the body. Its chemical formula is C21H25ClN2O3S, and it has a molecular weight of approximately 388.96 g/mol. Cetirizine is typically administered in oral form and is known for its relatively long duration of action, making it effective for once-daily dosing. The substance is generally well-tolerated, although some individuals may experience side effects such as drowsiness, dry mouth, or gastrointestinal disturbances. Cetirizine is also used in the management of chronic urticaria (hives) and is available in various formulations, including tablets, syrup, and chewable forms. Its safety profile and efficacy make it a popular choice for treating allergic conditions.
Formula:C21H25ClN2O3
InChI:InChI=1/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)
InChI key:InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N
SMILES:C(N1CCN(CCOCC(O)=O)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3
Synonyms:
  • 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid
  • Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
  • Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
  • 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid
  • Cetirizine
  • (±)-Cetirizine
  • (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)aceticacid
  • Zirtek
  • Zyrlex
  • (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-aceticaci
  • See more synonyms
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