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CAS 83881-52-1

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Cetirizine hydrochloride

Description:
Cetirizine hydrochloride is an antihistamine commonly used to alleviate allergy symptoms such as sneezing, runny nose, and itching. It is a second-generation antihistamine, which means it is less likely to cause sedation compared to first-generation antihistamines. Cetirizine works by selectively inhibiting the H1 histamine receptor, thereby reducing the effects of histamine in the body. The substance is typically administered orally and is available in various forms, including tablets and syrup. Its chemical formula is C21H25ClN2O3S, and it has a molecular weight of approximately 388.96 g/mol. Cetirizine hydrochloride is known for its relatively long duration of action, allowing for once-daily dosing. It is generally well-tolerated, though some individuals may experience side effects such as drowsiness, dry mouth, or gastrointestinal disturbances. Additionally, cetirizine is contraindicated in certain populations, such as those with severe renal impairment, and should be used with caution in pregnant or breastfeeding women.
Formula:C21H25ClN2O3·2ClH
InChI:InChI=1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
InChI key:InChIKey=PGLIUCLTXOYQMV-UHFFFAOYSA-N
SMILES:C(N1CCN(CCOCC(O)=O)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3.Cl
Synonyms:
  • (2-{4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazin-1-Yl}Ethoxy)Acetic Acid Dihydrochloride
  • 2-(2-[4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl]ethoxy)acetic acid dihydrochloride
  • 2-(2-{4-[(4-Chlorophenyl)(phenyl)-methyl]piperazino}ethoxy)acetic acid dihydrochloride
  • Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride (1:2)
  • Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, dihydrochloride
  • Alercet
  • Alerid
  • Alerlisin
  • Cesta
  • Cetiriz
  • See more synonyms
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