CAS 83930-13-6

Somatorelin

Description:

Somatorelin, also known as growth hormone-releasing hormone (GHRH), is a synthetic peptide that stimulates the release of growth hormone from the anterior pituitary gland. It is composed of 29 amino acids and is characterized by its role in regulating growth and metabolism. Somatorelin acts on specific receptors in the pituitary gland, promoting the secretion of growth hormone, which in turn influences various physiological processes, including growth, cell reproduction, and regeneration. The substance is often utilized in clinical settings to assess pituitary function and diagnose growth hormone deficiencies. Its pharmacological effects include potential applications in treating conditions related to growth hormone deficiency, such as growth disorders in children and adults. Somatorelin is typically administered via injection, and its stability and efficacy can be influenced by factors such as formulation and storage conditions. As with any peptide, careful consideration of dosage and potential side effects is essential in its therapeutic use.

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

InChI: InChI=1/C215H358N72O66S/c1-24-106(15)166(285-174(318)112(21)251-193(337)145(91-163(309)310)270-173(317)109(18)249-175(319)119(218)86-115-49-53-117(293)54-50-115)208(352)278-142(87-114-39-27-26-28-40-114)200(344)287-168(113(22)292)209(353)279-144(90-157(225)301)199(343)283-150(99-291)204(348)274-141(88-116-51-55-118(294)56-52-116)197(341)261-126(47-37-78-243-214(235)236)181(325)260-122(42-30-32-73-217)192(336)284-165(105(13)14)206(350)277-137(82-101(5)6)178(322)247-95-160(304)253-129(58-65-152(220)296)185(329)272-140(85-104(11)12)196(340)282-147(96-288)202(346)252-111(20)172(316)256-124(45-35-76-241-212(231)232)180(324)259-121(41-29-31-72-216)184(328)271-139(84-103(9)10)195(339)273-138(83-102(7)8)194(338)266-133(61-68-155(223)299)190(334)276-146(92-164(311)312)201(345)286-167(107(16)25-2)207(351)268-135(71-80-354-23)191(335)281-148(97-289)203(347)262-127(48-38-79-244-215(237)238)182(326)264-131(59-66-153(221)297)187(331)263-128(57-64-151(219)295)177(321)246-94-159(303)254-130(62-69-161(305)306)186(330)280-149(98-290)205(349)275-143(89-156(224)300)198(342)267-132(60-67-154(222)298)188(332)265-134(63-70-162(307)308)189(333)258-120(43-33-74-239-210(227)228)176(320)245-93-158(302)248-108(17)170(314)255-123(44-34-75-240-211(229)230)179(323)250-110(19)171(315)257-125(46-36-77-242-213(233)234)183(327)269-136(169(226)313)81-100(3)4/h26-28,39-40,49-56,100-113,119-150,165-168,288-294H,24-25,29-38,41-48,57-99,216-218H2,1-23H3,(H2,219,295)(H2,220,296)(H2,221,297)(H2,222,298)(H2,223,299)(H2,224,300)(H2,225,301)(H2,226,313)(H,245,320)(H,246,321)(H,247,322)(H,248,302)(H,249,319)(H,250,323)(H,251,337)(H,252,346)(H,253,304)(H,254,303)(H,255,314)(H,256,316)(H,257,315)(H,258,333)(H,259,324)(H,260,325)(H,261,341)(H,262,347)(H,263,331)(H,264,326)(H,265,332)(H,266,338)(H,267,342)(H,268,351)(H,269,327)(H,270,317)(H,271,328)(H,272,329)(H,273,339)(H,274,348)(H,275,349)(H,276,334)(H,277,350)(H,278,352)(H,279,353)(H,280,330)(H,281,335)(H,282,340)(H,283,343)(H,284,336)(H,285,318)(H,286,345)(H,287,344)(H,305,306)(H,307,308)(H,309,310)(H,311,312)(H4,227,228,239)(H4,229,230,240)(H4,231,232,241)(H4,233,234,242)(H4,235,236,243)(H4,237,238,244)

Synonyms:

• Growth Hormone Releasing Factor, Human
• GRF (1-44) (human)
• H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2

GRF (human)

CAS: 83930-13-6

GRF is the hypothalamic peptide hormone that specifically stimulates synthesis and release of the growth hormone by somatotropic cells of the anterior pituitary gland.

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: 98.1%

Color and Shape: White Lyophilisate

Molecular weight: 5039.72

Ref: 01-4011472

Human growth hormone-releasing factor

CAS: 83930-13-6

GHRH from the hypothalamus prompts the pituitary to produce/release GH by attaching to the GHRHR.

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 5039.65

Ref: TM-TP1155

GRF (human) Acetate

CAS: 83930-13-6

Ref: 7W-GX0567

GRF (Human)

CAS: 83930-13-6

Growth hormone-releasing factor (GRF) or GHRH (growth hormone-releasing hormone).Binds to the growth hormone-releasing hormone receptor (GHRH-R), causing growth hormone secretion.porcine: H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGERNQEQGARVRL-NH2bovine:  H-YADAIFTNSYRKVLGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2ovine:    H-YADAIFTNSYRKILGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2human:  H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: Min. 95%

Molecular weight: 5,039.7 g/mol

Ref: 3D-PGR-4127-S

GRF (Human)

CAS: 83930-13-6

Growth hormone-releasing factor (GRF) or GHRH (growth hormone-releasing hormone).Binds to the growth hormone-releasing hormone receptor (GHRH-R), causing growth hormone secretion. See also GRF (1-29); sermorelin, a shorter fragment. Sequence alignments: porcine: H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGERNQEQGARVRL-NH2bovine:  H-YADAIFTNSYRKVLGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2ovine:    H-YADAIFTNSYRKILGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2human:  H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: Min. 95%

Molecular weight: 5,039.7 g/mol

Ref: 3D-PGR-4127-V

GRF (human) acetate salt

CAS: 83930-13-6

Growth hormone-releasing factor (GRF) or GHRH (growth hormone-releasing hormone).Binds to the growth hormone-releasing hormone receptor (GHRH-R), causing growth hormone secretion.porcine: H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGERNQEQGARVRL-NH2bovine:  H-YADAIFTNSYRKVLGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2ovine:    H-YADAIFTNSYRKILGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2human:  H-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 5,039.65 g/mol

Ref: 3D-FG109065

Somatoliberin (human pancreatic islet)

CAS: 83930-13-6

Formula: C₂₁₅H₃₅₈N₇₂O₆₆S

Purity: 95%

Color and Shape: Solid

Molecular weight: 5039.6508

Ref: IN-DA01CPAA