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CAS 84-02-6

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Prochlorperazine maleate

Description:
Prochlorperazine maleate is a pharmaceutical compound primarily used as an antipsychotic and antiemetic agent. It belongs to the class of drugs known as phenothiazines, which are characterized by their ability to block dopamine receptors in the brain, thereby helping to manage symptoms of schizophrenia and severe anxiety. The maleate salt form enhances its solubility and stability. Prochlorperazine maleate is typically administered orally or via injection, and it is effective in controlling nausea and vomiting, particularly in patients undergoing chemotherapy or surgery. The compound exhibits a range of side effects, including sedation, dry mouth, and potential extrapyramidal symptoms due to its dopaminergic activity. It is essential to monitor patients for these effects, especially during prolonged use. Additionally, caution is advised in patients with certain medical conditions, such as cardiovascular disorders or those taking other medications that may interact with prochlorperazine. Overall, it is a valuable medication in psychiatric and medical settings, but it requires careful management to mitigate potential adverse effects.
Formula:C20H24ClN3S·2C4H4O4
InChI:InChI=1S/C20H24ClN3S.C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key:InChIKey=ZYSCHNVPUOSLNC-BTJKTKAUSA-N
SMILES:C(=C\C(O)=O)\C(O)=O.C(CCN1CCN(C)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3
Synonyms:
  • 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, (2Z)-2-butenedioate (1:2)
  • 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-, (Z)-2-butenedioate (1:2)
  • 2-Chloro-10-(3-(4-methylpiperazin-1-yl)propyl)-10H-phenothiazine dimaleate
  • 2-Chloro-10-[3-(4-Methylpiperazin-1-Yl)Propyl]Phenothiazine
  • 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine dimaleate
  • 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine di[(2Z)-but-2-enedioate]
  • Buccastem
  • But-2-Enedioic Acid
  • Compazine
  • Emetiral
  • See more synonyms
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