CAS 84-36-6

Syrosingopine

Description:

Syrosingopine is an organic compound classified as an alkaloid, primarily derived from the plant species *Syrosingopine* and related plants. It is known for its structural complexity, featuring a bicyclic framework that includes a piperidine ring. The compound exhibits a range of biological activities, including potential analgesic and antihypertensive effects, making it of interest in pharmacological research. Syrosingopine is typically characterized by its solubility in organic solvents, while its solubility in water is limited. The compound has a relatively low molecular weight and is often studied for its interactions with various biological targets, including receptors and enzymes. Its chemical properties, such as melting point and boiling point, are influenced by its molecular structure and functional groups. As with many alkaloids, syrosingopine may also exhibit chiral properties, leading to different biological activities depending on its stereochemistry. Overall, syrosingopine represents a significant area of study in medicinal chemistry and natural product research.

Formula: C₃₅H₄₂N₂O₁₁

InChI: InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1

InChI key: InChIKey=ZCDNRPPFBQDQHR-SSYATKPKSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Synonyms:

• (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(éthoxycarbonyl)oxy]-3,5-diméthoxybenzoyl}oxy)-2,11-diméthoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodécahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoléine-1-carboxylate de méthyle
• (3Bêta,16Bêta,17Alpha,18Bêta,20Alpha)-18-({4-[(Éthoxycarbonyl)Oxy]-3,5-Diméthoxybenzoyl}Oxy)-11,17-Diméthoxyyohimban-16-Carboxylate De Méthyle
• (3b,16b,17a,18b,20a)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic Acid Methyl Ester
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester)
• Carbethoxysyringoyl Methyl Reserpate
• Carbethoxysyringoyl methylreserpate
• Hf 41T
• Isotense
• Londomin
• Methyl (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-({[4-{[(Ethyloxy)Carbonyl]Oxy}-3,5-Bis(Methyloxy)Phenyl]Carbonyl}Oxy)-11,17-Bis(Methyloxy)Yohimban-16-Carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-[({4-[(Ethoxycarbonyl)Oxy]-3,5-Dimethoxyphenyl}Carbonyl)Oxy]-11,17-Dimethoxyyohimban-16-Carboxylate
• Methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-11,17-dimethoxyyohimban-16-carboxylate
• Methyl carbethoxysyringoyl reserpate
• Methyl reserpate ester of syringic acid ethyl carbonate
• Methyl-(1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isochinolin-1-carboxylat
• NSC 77030
• Raunova
• Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate
• Seniramin
• Singoserp
• Siringina
• Sml 1908
• Su 3118
• Syringic acid ethyl carbonate ester with methyl reserpate
• Syringopine
• Syrosingopin

Syrosingopine

CAS: 84-36-6

Syrosingopine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₃₅H₄₂N₂O₁₁

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 666.73

Ref: 11-1691

Syrosingopine

CAS: 84-36-6

Syrosingopine

Purity: ≥98%

Molecular weight: 666.71g/mol

Ref: 54-BUP07583

Syrosingopine

CAS: 84-36-6

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.

Formula: C₃₅H₄₂N₂O₁₁

Purity: 99.25% - 99.78%

Color and Shape: Solid

Molecular weight: 666.71

Ref: TM-TN2252

Syrosingopine

Controlled Product

CAS: 84-36-6

Applications Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.
References Woods, J. W.; et al.: Journal of Clinical Investigation, 39, 1813 (1960).

Formula: C₃₅H₄₂N₂O₁₁

Purity: >90%

Color and Shape: Neat

Molecular weight: 666.71

Ref: TR-S920068

Syrosingopine

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Formula: C₃₅H₄₂N₂O₁₁

Purity: Min. 90 Area-%

Color and Shape: White Powder

Molecular weight: 666.71 g/mol

Ref: 3D-FS65931

Syrosingopine - Bio-X ™

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Formula: C₃₅H₄₂N₂O₁₁

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 666.72 g/mol

Ref: 3D-BS300129

SYROSINGOPINE

CAS: 84-36-6

Formula: C₃₅H₄₂N₂O₁₁

Purity: %

Color and Shape: Solid

Molecular weight: 666.7148

Ref: IN-DA00G2SK

Syrosingopine

CAS: 84-36-6

Color and Shape: Neat

Ref: 61-FOR1970.00