CAS 84100-84-5

2,3,3-Trimethyl-3H-indole-5-carboxylic acid

Description:

2,3,3-Trimethyl-3H-indole-5-carboxylic acid is an organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This compound features three methyl groups at the 2 and 3 positions of the indole ring, contributing to its unique properties. The presence of a carboxylic acid functional group at the 5 position enhances its acidity and solubility in polar solvents. This compound is typically used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its molecular structure allows for potential interactions with biological systems, making it of interest in medicinal chemistry. Additionally, the presence of multiple methyl groups can influence its steric and electronic properties, affecting its reactivity and stability. As with many indole derivatives, it may exhibit interesting biological activities, although specific applications would depend on further research and characterization.

Formula: C₁₂H₁₃NO₂

InChI: InChI=1S/C12H13NO2/c1-7-12(2,3)9-6-8(11(14)15)4-5-10(9)13-7/h4-6H,1-3H3,(H,14,15)

InChI key: InChIKey=QUDAPQXQGBIUAR-UHFFFAOYSA-N

SMILES: CC1(C)C=2C(N=C1C)=CC=C(C(O)=O)C2

Synonyms:

• 2,3,3-Trimethyl-5-carboxyindolenine
• 5-Carboxyl-2,3,3-trimethyl-3H-indolenine
• 3H-Indole-5-carboxylic acid, 2,3,3-trimethyl-
• 2,3,3-Trimethyl-3H-indole-5-carboxylic acid

3H-Indole-5-carboxylicacid, 2,3,3-trimethyl-

CAS: 84100-84-5

Formula: C₁₂H₁₃NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 203.2371

Ref: IN-DA004PVS

2,3,3-Trimethyl-3H-indole-5-carboxylic acid

CAS: 84100-84-5

2,3,3-Trimethyl-3H-indole-5-carboxylic acid

Purity: 97%

Molecular weight: 203.24g/mol

Ref: 54-OR40717

2,3,3-Trimethyl-5-carboxyindolenine

Controlled Product

CAS: 84100-84-5

Applications Intermediate in the synthesis of cyanine dyes for fluorescence imaging of tumor hypoxia and as contrast agents for near-IR tumor imaging.
References Pavlik, C. et al.; Dyes Pigments 89, 9 (2010)

Formula: C₁₂H₁₃NO₂

Color and Shape: Neat

Molecular weight: 203.24

Ref: TR-T795970

2,3,3-Trimethyl-3H-indole-5-carboxylic acid

CAS: 84100-84-5

Formula: C₁₂H₁₃NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 203.241

Ref: 10-F080166

2,3,3-Trimethyl-5-carboxyindolenine

CAS: 84100-84-5

2,3,3-Trimethyl-5-carboxyindolenine (TMCI) is a fluorescent probe that can be used for the detection of hypoxic tumor tissue. It is a fluorimetric compound that reacts with nucleophilic sites on proteins and other functional groups to form conjugates. TMCI has been shown to react with cyanines, fluoroalkyl esters, and other compounds bearing electron-donating substituents. The optimum concentration of TMCI is between 0.1 and 1 mM in PBS buffer at pH 7.4 at 37°C. This probe is also sensitive to changes in its environment such as pH or temperature. TMCI has been shown to react with 2-nitroimidazole and unsymmetrical indolsium complexes, which are used as optical sensors for oxygen concentration measurements.

Formula: C₁₂H₁₃NO₂

Purity: Min. 95%

Molecular weight: 203.24 g/mol

Ref: 3D-JDA10084