CAS 84104-71-2

Wilforlide A

Description:

Wilforlide A is a natural product classified as a terpenoid, specifically a type of sesquiterpene lactone. It is derived from the plant species Wilfordia species, which is known for its medicinal properties. The compound is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Wilforlide A has garnered interest in the field of pharmacology due to its potential anti-inflammatory, anti-tumor, and antimicrobial properties. Its mechanism of action may involve the modulation of various cellular pathways, although detailed studies are ongoing to fully elucidate its effects. Additionally, the compound's solubility and stability can vary depending on the solvent and environmental conditions, which are important factors to consider in both research and potential therapeutic applications. Overall, Wilforlide A represents a promising area of study within natural product chemistry and drug development.

Formula: C₃₀H₄₆O₃

InChI: InChI=1/C30H46O3/c1-25(2)20-10-13-30(7)21(28(20,5)12-11-22(25)31)9-8-18-19-16-26(3)17-23(33-24(26)32)27(19,4)14-15-29(18,30)6/h8,19-23,31H,9-17H2,1-7H3/t19-,20-,21+,22-,23-,26-,27+,28-,29+,30+/m0/s1

InChI key: InChIKey=HHQJBWYXBWOFJY-YLXTXNMFSA-N

SMILES: C[C@]12C([C@]3([C@@](C)(CC1)[C@@]4(C[C@](C)(C3)C(=O)O4)[H])[H])=CC[C@]5([C@@]2(C)CC[C@@]6([C@]5(C)CC[C@H](O)C6(C)C)[H])[H]

Synonyms:

• (-)-Abruslactone A
• 4,2-(Epoxymethano)picene, olean-12-en-29-oic acid deriv.
• Olean-12-En-29-One, 22,29-Epoxy-3-Hydroxy-, (3Beta,22Alpha)-
• Olean-12-en-29-oic acid, 3,22-dihydroxy-, γ-lactone, (3β,20α,22α)-
• Regelide
• Wilforlide A
• (3beta,22alpha)-3-Hydroxy-22,29-epoxyolean-12-en-29-one
• WOLFORLIDE A
• Olean-12-en-29-oicacid, 3,22-dihydroxy-, γ-lactone, (3β,20α,22α)-
• Wilforlide
• 4,2-(Epoxymethano)picene, olean-12-en-29-oicacid deriv

Wilforlide A

CAS: 84104-71-2

Formula: C₃₀H₄₆O₃

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 454.70

Ref: 3B-W0011

Wilforlide A

CAS: 84104-71-2

Wilforlide A

Formula: C₃₀H₄₆O₃

Molecular weight: 454.68444

Ref: 54-BI12146

Wilforlide A

CAS: 84104-71-2

Wilforlide A

Formula: C₃₀H₄₆O₃

Purity: ≥95%

Molecular weight: 454.68

Ref: 54-BUP00151

Wilforlide A

CAS: 84104-71-2

Formula: C₃₀H₄₆O₃

Molecular weight: 454.70

Ref: 7W-GY3165

Wilforlide A (Standard)

CAS: 84104-71-2

Wilforlide A (Standard) is a reference standard of Wilforlide A intended for quantitative analysis, quality control, and related biochemical research applications.

Formula: C₃₀H₄₆O₄

Molecular weight: 470.6838

Ref: TM-TMSM-4106

Wilforlide A

CAS: 84104-71-2

Wilforlide A is a quality control standard of Tripterygium Glycosides that be listed in Drug Standard of Ministry of Public Health of the People's Republic of China. Wilforlide A has obvious anti-inflammatory effects.

Formula: C₃₀H₄₆O₃

Purity: 95%~99%

Molecular weight: 454.695

Ref: BP-BP1452

Wilforlide A

CAS: 84104-71-2

Formula: C₃₀H₄₆O₃

Purity: %

Color and Shape: Solid

Molecular weight: 454.6844

Ref: IN-DA00G3A8

Wilforlide A

CAS: 84104-71-2

Wilforlide A (3-Epiabruslactone A) is a natural product, separated from the ethanolic extract of tripterygium wilfordii.

Formula: C₃₀H₄₆O₄

Purity: 98.41% - ≥95%

Color and Shape: Solid

Molecular weight: 470.6838

Ref: TM-T3382

Wilforlide A

CAS: 84104-71-2

Lactone

Formula: C₃₀H₄₆O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 454.7

Ref: 5G-80555

Wilforlide A

CAS: 84104-71-2

Wilforlide A is a novel anticancer drug that inhibits the growth of cancer cells by inhibiting amino transferase and blocking the synthesis of DNA. Wilforlide A has synergistic effects when used in combination with tripterygium wilfordii, a Chinese herb, and moronic acid, an extract from Tripterygium wilfordii. Wilforlide A also has anti-inflammatory properties and can be used to treat autoimmune diseases. The efficacy of Wilforlide A was evaluated using surface methodology on human skin squamous carcinoma samples. It was found that Wilforlide A had no cytotoxicity when applied to these cells. In addition, it inhibited tumor growth in mice inoculated with human squamous carcinoma cells. These findings show that Wilforlide A is a potential candidate for treating squamous carcinoma patients.

Formula: C₃₀H₄₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 454.68 g/mol

Ref: 3D-FW65700