CAS 84117-86-2

1H-Indole-2-carboxylicacid, 1,1-dimethylethyl ester

Description:

1H-Indole-2-carboxylic acid, 1,1-dimethylethyl ester, also known by its CAS number 84117-86-2, is an organic compound characterized by its indole structure, which consists of a fused benzene and pyrrole ring. This compound features a carboxylic acid functional group that is esterified with a tert-butyl group, contributing to its stability and lipophilicity. Typically, indole derivatives exhibit a range of biological activities, including antimicrobial, anti-inflammatory, and anticancer properties, making them of interest in pharmaceutical research. The presence of the tert-butyl ester enhances its solubility in organic solvents, facilitating its use in various chemical reactions and applications. Additionally, the compound may undergo hydrolysis to release the corresponding indole-2-carboxylic acid, which can further participate in biochemical pathways. Its structural characteristics, including the indole core and ester functionality, make it a versatile compound in synthetic organic chemistry and medicinal chemistry.

Formula: C₁₃H₁₅NO₂

InChI: InChI=1S/C13H15NO2/c1-13(2,3)16-12(15)11-8-9-6-4-5-7-10(9)14-11/h4-8,14H,1-3H3

InChI key: FMNXFKVTZJWOAD-UHFFFAOYSA-N

SMILES: CC(C)(C)OC(=O)C1=CC2=CC=CC=C2N1

Synonyms:

• Indole-2-carboxylicacid tert-Butyl ester
• tert-Butyl 1H-indole-2-carboxylate

Indole-2-carboxylic acid tert-butyl ester

CAS: 84117-86-2

Indole-2-carboxylic acid tert-butyl ester is a synthetic compound that exhibits potent antiapoptotic activity. It has been shown to inhibit the bcl-2 family of proteins, which are involved in the regulation of apoptosis. Indole-2-carboxylic acid tert-butyl ester has also been shown to inhibit the growth of cancer cells in cell culture and induce apoptosis in these cells. This compound also inhibits the production of furan, which is a functional group found on some carcinogenic chemicals. Indole-2-carboxylic acid tert-butyl ester is an inhibitor of Bax protein, a proapoptotic protein that plays a role in regulating cell death.

Formula: C₁₃H₁₅NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 217.26 g/mol

Ref: 3D-FI172363