CAS 841301-32-4
:Amenamevir
Description:
Amenamevir, with the CAS number 841301-32-4, is an antiviral compound primarily investigated for its efficacy against herpes simplex virus (HSV) infections. It belongs to the class of drugs known as helicase-primase inhibitors, which function by disrupting the viral replication process. Amenamevir exhibits a unique mechanism of action by targeting the viral helicase-primase complex, thereby inhibiting the unwinding of viral DNA and preventing the synthesis of new viral particles. This compound has shown promise in clinical studies for treating herpes zoster and other herpesvirus-related conditions. Amenamevir is characterized by its relatively low toxicity profile and favorable pharmacokinetic properties, which may allow for convenient dosing regimens. Additionally, it has been noted for its potential to reduce the duration and severity of herpes outbreaks. As with any antiviral agent, ongoing research is essential to fully understand its efficacy, safety, and potential applications in broader antiviral therapy.
Formula:C24H26N4O5S
InChI:InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)
InChI key:InChIKey=MNHNIVNAFBSLLX-UHFFFAOYSA-N
SMILES:N(C(=O)C1CCS(=O)(=O)CC1)(CC(NC2=CC=C(C=C2)C=3N=CON3)=O)C4=C(C)C=CC=C4C
Synonyms:- N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide
- 2H-Thiopyran-4-carboxamide, N-(2,6-dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-, 1,1-dioxide
- Amenamevir
- N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide
- N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide
- ASP 2151
- Amenamevir(ASP 2151)
- ASP-2151
- Amcnamevir
- Amenamevir (ASP2151)
- ASP 2151 (Amenamevir)
- ASP2151;ASP 2151;ASP-2151
- See more synonyms
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Amenamevir
CAS:N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxideFormula:C24H26N4O5SPurity:99%Molecular weight:482.55Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:White SolidMolecular weight:482.552Amenamevir
CAS:Amenamevir is an antiviral medication, which is synthesized from a chemical source. Its mode of action involves the selective inhibition of the helicase-primase complex of the varicella-zoster virus (VZV), thereby disrupting the viral DNA replication process. By specifically targeting this enzyme complex, Amenamevir impairs the viral replication machinery, leading to a reduction in viral load and amelioration of symptoms associated with infection.
Formula:C24H26N4O5SPurity:Min. 95%Molecular weight:482.55 g/mol
