CAS 841302-25-8

(2S)-1-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)acetyl]-2-pyrrolidinecarbonitrile

Formula: C₁₇H₂₅N₃O₂

InChI: InChI=1S/C17H25N3O2/c18-9-13-2-1-3-20(13)15(21)14(19)16-5-11-4-12(6-16)8-17(22,7-11)10-16/h11-14,22H,1-8,10,19H2/t11?,12?,13-,14+,16?,17?/m0/s1

InChI key: InChIKey=OHUOCCZGTKZOSF-GKNBTTNJSA-N

SMILES: [C@H](C(=O)N1[C@H](C#N)CCC1)(N)C23CC4(O)CC(C2)CC(C3)C4

Synonyms:

• (2S)-1-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-pyrrolidinecarbonitrile
• 2-Pyrrolidinecarbonitrile, 1-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (2S)-
• 2-Pyrrolidinecarbonitrile, 1-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (2S)-

Des-cyclopropyl Saxagliptin

Controlled Product

CAS: 841302-25-8

Applications Des-cyclopropyl Saxagliptin is an impurity of the drug Saxagliptin (S143500), a potent and selective reversible inhibitor of dipeptidyl peptidase-4.
References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),

Formula: C₁₇H₂₅N₃O₂

Color and Shape: Neat

Molecular weight: 303.399

Ref: TR-D291908