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CAS 84145-89-1

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Almoxatone

Description:
Almoxatone is a chemical compound classified as a monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. It functions by inhibiting the activity of monoamine oxidase enzymes, which are responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters, potentially alleviating depressive symptoms. Almoxatone is known for its selectivity towards the MAO-B isoform, which may contribute to its therapeutic effects and side effect profile. The compound is typically administered orally and has been studied for its efficacy and safety in various clinical settings. As with other MAOIs, patients taking Almoxatone must adhere to dietary restrictions to avoid hypertensive crises caused by the consumption of tyramine-rich foods. Overall, Almoxatone represents a significant option in the pharmacological management of mood disorders, although its use may be limited by potential interactions with other medications and dietary components.
Formula:C18H19ClN2O3
InChI:InChI=1S/C18H19ClN2O3/c1-20-10-17-11-21(18(22)24-17)15-5-7-16(8-6-15)23-12-13-3-2-4-14(19)9-13/h2-9,17,20H,10-12H2,1H3/t17-/m1/s1
InChI key:InChIKey=KYXSTSXVEXKFJI-QGZVFWFLSA-N
SMILES:O=C1N(C[C@@H](CNC)O1)C2=CC=C(OCC3=CC(Cl)=CC=C3)C=C2
Synonyms:
  • ( )-(R)-3-(p-((m-Chlorobenzyl)oxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinone
  • ( -)-(R)-3-(4-(2-Chlorbenzyloxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinon
  • (5R)-3-[4-[(3-Chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-2-oxazolidinone
  • (5R)-3-{4-[(3-chlorobenzyl)oxy]phenyl}-5-[(methylamino)methyl]-1,3-oxazolidin-2-one
  • 2-Oxazolidinone, 3-[4-[(3-chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-, (5R)-
  • 2-Oxazolidinone, 3-[4-[(3-chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-, (R)-
  • Almoxaton
  • Almoxatone [INN]
  • Almoxatonum
  • Md 240928
  • See more synonyms
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Found 2 products.
  • Almoxatone
    Biosynth
    + Info

    Almoxatone

    CAS:
    <p>Almoxatone is a pyrazole derivative that inhibits the enzyme catalysis of monoamine oxidase A and B. It has an inhibitory effect on dopamine and norepinephrine, which are neurotransmitters in the central nervous system. Almoxatone has been shown to have a beneficial effect on Parkinson's disease and other types of movement disorders. This drug also has a strong inhibitory effect on inflammatory diseases such as rheumatoid arthritis and ulcerative colitis, which may be due to its ability to inhibit the production of cytokines such as TNF-α. In vitro assays have demonstrated that this drug does not cause damage to dopamine neurons in the striatum.</p>
    Formula:C18H19ClN2O3
    Purity:Min. 95%
    Molecular weight:346.81 g/mol

    Ref: 3D-FA170158

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  • Almoxatone
    Targetmol
    + Info

    Almoxatone

    CAS:
    Almoxatone, also known as MD 780236, is a monoamine oxidase (MAO) inhibitor.
    Formula:C18H19ClN2O3
    Color and Shape:Solid
    Molecular weight:346.81

    Ref: TM-T68593