CymitQuimica logo

CAS 84145-89-1

:

Almoxatone

Description:
Almoxatone is a chemical compound classified as a monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. It functions by inhibiting the activity of monoamine oxidase enzymes, which are responsible for the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This inhibition leads to increased levels of these neurotransmitters, potentially alleviating depressive symptoms. Almoxatone is known for its selectivity towards the MAO-B isoform, which may contribute to its therapeutic effects and side effect profile. The compound is typically administered orally and has been studied for its efficacy and safety in various clinical settings. As with other MAOIs, patients taking Almoxatone must adhere to dietary restrictions to avoid hypertensive crises caused by the consumption of tyramine-rich foods. Overall, Almoxatone represents a significant option in the pharmacological management of mood disorders, although its use may be limited by potential interactions with other medications and dietary components.
Formula:C18H19ClN2O3
InChI:InChI=1S/C18H19ClN2O3/c1-20-10-17-11-21(18(22)24-17)15-5-7-16(8-6-15)23-12-13-3-2-4-14(19)9-13/h2-9,17,20H,10-12H2,1H3/t17-/m1/s1
InChI key:InChIKey=KYXSTSXVEXKFJI-QGZVFWFLSA-N
SMILES:O=C1N(C[C@@H](CNC)O1)C2=CC=C(OCC3=CC(Cl)=CC=C3)C=C2
Synonyms:
  • ( )-(R)-3-(p-((m-Chlorobenzyl)oxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinone
  • ( -)-(R)-3-(4-(2-Chlorbenzyloxy)phenyl)-5-((methylamino)methyl)-2-oxazolidinon
  • (5R)-3-[4-[(3-Chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-2-oxazolidinone
  • (5R)-3-{4-[(3-chlorobenzyl)oxy]phenyl}-5-[(methylamino)methyl]-1,3-oxazolidin-2-one
  • 2-Oxazolidinone, 3-[4-[(3-chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-, (5R)-
  • 2-Oxazolidinone, 3-[4-[(3-chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-, (R)-
  • Almoxaton
  • Almoxatone [INN]
  • Almoxatonum
  • Md 240928
  • See more synonyms
Found 1 products.