CAS 84236-26-0

(+)-Bromonaproxen

Description:

(+)-Bromonaproxen is a non-steroidal anti-inflammatory drug (NSAID) that is a derivative of naproxen, characterized by the presence of a bromine atom in its structure. It exhibits anti-inflammatory, analgesic, and antipyretic properties, making it effective in treating conditions such as arthritis, muscle pain, and fever. The compound is known for its chiral nature, with the (+) designation indicating its specific enantiomer, which is typically more active in biological systems. (+)-Bromonaproxen works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. Its pharmacokinetics involve oral administration, with absorption occurring in the gastrointestinal tract, and it is metabolized primarily in the liver. The substance is generally well-tolerated, although potential side effects may include gastrointestinal discomfort, cardiovascular risks, and allergic reactions. As with other NSAIDs, caution is advised in patients with pre-existing conditions or those taking other medications that may interact.

Formula: C₁₄H₁₃BrO₃

InChI: InChI=1S/C14H13BrO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1

InChI key: InChIKey=JZRWXNBIQCMXSU-QMMMGPOBSA-N

SMILES: BrC=1C2=C(C=C([C@@H](C(O)=O)C)C=C2)C=CC1OC

Synonyms:

• (+)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid
• (+)-Bromonaproxen
• (5-Bromo-6-Methoxynaphthalen-1-Yl)Acetic Acid - Methane (1:1)
• (S)-2-(5-Bromo-6-methoxy-2-naphthyl)propanoic acid
• (S)-5-Bromo-6-methoxy-alpha-methylnaphthalene-1-acetic acid
• (αS)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid
• 2-Naphthaleneacetic acid, 5-bromo-6-methoxy-α-methyl-, (S)-
• 2-Naphthaleneacetic acid, 5-bromo-6-methoxy-α-methyl-, (αS)-
• S-(+)-2-(5-Bromo-6-Methoxy-2-Naphthyl)propionic Acid

Bromo Naproxen ((2S)-2-(5-Bromo-6-methoxynaphthalen-2-yl)propanoic acid)

CAS: 84236-26-0

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

Formula: C₁₄H₁₃BrO₃

Color and Shape: White Powder

Molecular weight: 308.00481

Ref: 45-1A10420

Naproxen EP Impurity C (5-Bromo Naproxen)

CAS: 84236-26-0

Formula: C₁₄H₁₃BrO₃

Color and Shape: White To Off-White Solid

Molecular weight: 309.16

Ref: 4Z-N-238

(2S)-2-(5-Bromo-6-methoxynaphthalen-2-yl)propanoic Acid (5-Bromonaproxen)

Controlled Product

CAS: 84236-26-0

Formula: C₁₄H₁₃BrO₃

Color and Shape: Neat

Molecular weight: 309.16

Ref: 86-MM0152.10

Naproxen EP Impurity C

CAS: 84236-26-0

Formula: C₁₄H₁₃BrO₃

Molecular weight: 309.16

Ref: ST-EA-CP-N2003

(S)-5-Bromo Naproxen

Controlled Product

CAS: 84236-26-0

Formula: C₁₄H₁₃BrO₃

Color and Shape: Neat

Molecular weight: 309.16

Ref: TR-B685895

Naproxen Impurity C

CAS: 84236-26-0

Naproxen Impurity C is an analytical impurity that is found in Naproxen. It is a white crystalline powder with a melting point of 210°C and an assay of 99%. It has been shown to be a metabolite of Naproxen, and may have therapeutic value for the treatment of pain, inflammation, or fever. The purity of this product has been verified by HPLC analysis.

Formula: C₁₄H₁₃BrO₃

Purity: Min. 95%

Molecular weight: 309.16 g/mol

Ref: 3D-IN181212