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CAS 84236-26-0

:

(+)-Bromonaproxen

Description:
(+)-Bromonaproxen is a non-steroidal anti-inflammatory drug (NSAID) that is a derivative of naproxen, characterized by the presence of a bromine atom in its structure. It exhibits anti-inflammatory, analgesic, and antipyretic properties, making it effective in treating conditions such as arthritis, muscle pain, and fever. The compound is known for its chiral nature, with the (+) designation indicating its specific enantiomer, which is typically more active in biological systems. (+)-Bromonaproxen works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. Its pharmacokinetics involve oral administration, with absorption occurring in the gastrointestinal tract, and it is metabolized primarily in the liver. The substance is generally well-tolerated, although potential side effects may include gastrointestinal discomfort, cardiovascular risks, and allergic reactions. As with other NSAIDs, caution is advised in patients with pre-existing conditions or those taking other medications that may interact.
Formula:C14H13BrO3
InChI:InChI=1S/C14H13BrO3/c1-8(14(16)17)9-3-5-11-10(7-9)4-6-12(18-2)13(11)15/h3-8H,1-2H3,(H,16,17)/t8-/m0/s1
InChI key:InChIKey=JZRWXNBIQCMXSU-QMMMGPOBSA-N
SMILES:BrC=1C2=C(C=C([C@@H](C(O)=O)C)C=C2)C=CC1OC
Synonyms:
  • (+)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid
  • (+)-Bromonaproxen
  • (5-Bromo-6-Methoxynaphthalen-1-Yl)Acetic Acid - Methane (1:1)
  • (S)-2-(5-Bromo-6-methoxy-2-naphthyl)propanoic acid
  • (S)-5-Bromo-6-methoxy-alpha-methylnaphthalene-1-acetic acid
  • (αS)-5-Bromo-6-methoxy-α-methyl-2-naphthaleneacetic acid
  • 2-Naphthaleneacetic acid, 5-bromo-6-methoxy-α-methyl-, (S)-
  • 2-Naphthaleneacetic acid, 5-bromo-6-methoxy-α-methyl-, (αS)-
  • S-(+)-2-(5-Bromo-6-Methoxy-2-Naphthyl)propionic Acid
Found 9 products.