CAS 84371-65-3

Mifepristone

Description:

Mifepristone, with the CAS number 84371-65-3, is a synthetic steroid compound primarily known for its use as an abortifacient and in the treatment of certain medical conditions such as Cushing's syndrome. It functions as a progesterone receptor antagonist, blocking the effects of progesterone, which is crucial for maintaining pregnancy. Mifepristone is characterized by its ability to induce uterine contractions and facilitate the expulsion of the embryo when used in combination with a prostaglandin. The compound is typically administered orally and has a relatively high bioavailability. Its chemical structure includes a 17β-hydroxy-11β-(4-dimethylaminophenyl)-18-oxa-19-norprogesterone framework, which contributes to its biological activity. Mifepristone is also noted for its potential side effects, which can include gastrointestinal disturbances, fatigue, and hormonal changes. Due to its significant impact on reproductive health, mifepristone is subject to strict regulatory controls in many countries.

Formula: C₂₉H₃₅NO₂

InChI: InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1

InChI key: InChIKey=VKHAHZOOUSRJNA-GCNJZUOMSA-N

SMILES: C[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(N(C)C)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C#CC)O)[H]

Synonyms:

• (11R,13S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
• (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one
• 17β-Hydroxy-11β-[4-(dimethylamino)-phenyl]-17α-(prop-1-ynyl)-estra-4,9-dien-3-one
• C 1073
• Cdb 2477
• Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)-, (11β,17β)-
• Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-, (11β,17β)-
• MTPill
• Mifegyne
• Mifeprex
• Mifepriston Dianhydride
• Mifestone
• Pencrofton
• R 38486
• Ru 38486
• Ru 486
• Ru 486-6

Mifepristone

CAS: 84371-65-3

Formula: C₂₉H₃₅NO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Green powder to crystal

Molecular weight: 429.60

Ref: 3B-M1732

Mifepristone 1.0 mg/ml in Acetonitrile

CAS: 84371-65-3

Color and Shape: Single Solution

Ref: 61-AMP1007.00-11

Mifepristone

CAS: 84371-65-3

Color and Shape: Neat

Ref: 61-FOR1007.00

Mifepristone

CAS: 84371-65-3

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₉H₃₅NO₂

Color and Shape: Yellow Powder

Molecular weight: 429.26678

Ref: 45-1443759

Mifepristone

CAS: 84371-65-3

Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!

Formula: C₂₉H₃₅NO₂

Purity: 98.9% - ≥95%

Color and Shape: Pale Yellow Solid

Molecular weight: 429.59

Ref: TM-T1102

(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one

CAS: 84371-65-3

Formula: C₂₉H₃₅NO₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 429.5937

Ref: IN-DA00359Q

Mifepristone-13C-d3

CAS: 84371-65-3

Formula: C₂₈₁₃CH₃₂D₃NO₂

Color and Shape: Yellow Solid

Molecular weight: 433.61

Ref: 4Z-M-2919

Mifepristone

CAS: 84371-65-3

Mifepristone

Purity: ≥95%

Molecular weight: 429.59g/mol

Ref: 54-BUP17060

Mifepristone

CAS: 84371-65-3

Mifepristone

Purity: 98%

Molecular weight: 429.59g/mol

Ref: 54-OR1024695

Mifepristone

CAS: 84371-65-3

Formula: C₂₉H₃₅NO₂

Purity: ≥ 98.0%

Color and Shape: Off-white to pale yellow or yellow powder

Molecular weight: 429.59

Ref: 7W-GP8226

Mifepristone

CAS: 84371-65-3

Formula: C₂₉H₃₅NO₂

Color and Shape: Pale Yellow Solid

Molecular weight: 429.60

Ref: 4Z-M-291

Mifepristone-d3

CAS: 84371-65-3

Formula: C₂₉H₃₂NO₂D₃

Molecular weight: 432.63

Ref: 4Z-M-292

Mifepristone

Controlled Product

CAS: 84371-65-3

Formula: C₂₉H₃₅NO₂

Color and Shape: Neat

Molecular weight: 429.59

Ref: 86-MM1007.00

Mifepristone-d3

Controlled Product

CAS: 84371-65-3

Applications A labelled progesterone receptor antagonist with partial agonist activity. Abortifacient.
References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)

Formula: C₂₉D₃H₃₂NO₂

Color and Shape: Light Yellow Solid

Molecular weight: 432.61

Ref: TR-M343977

Mifepristone

Controlled Product

CAS: 84371-65-3

Applications Mifepristone is a progesterone receptor antagonist with partial agonist activity. Abortifacient.
References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)

Formula: C₂₉H₃₅NO₂

Color and Shape: White To Light Yellow

Molecular weight: 429.59

Ref: TR-M343975

Mifepristone

Controlled Product

CAS: 84371-65-3

Progesterone and glucocorticoid receptor antagonist

Formula: C₂₉H₃₅NO₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 429.59 g/mol

Ref: 3D-FM26002

Mifepristone

CAS: 84371-65-3

Purity: 99%

Molecular weight: 429.6040039

Ref: 10-F795098

4,5-Dihydro-5α-hydroxy-mifepristone

Controlled Product

CAS: 84371-65-3

Formula: C₂₉H₃₇NO₃

Color and Shape: Neat

Molecular weight: 447.61

Ref: TR-D678978