CAS 84371-65-3
:Mifepristone
Description:
Mifepristone, with the CAS number 84371-65-3, is a synthetic steroid compound primarily known for its use as an abortifacient and in the treatment of certain medical conditions such as Cushing's syndrome. It functions as a progesterone receptor antagonist, blocking the effects of progesterone, which is crucial for maintaining pregnancy. Mifepristone is characterized by its ability to induce uterine contractions and facilitate the expulsion of the embryo when used in combination with a prostaglandin. The compound is typically administered orally and has a relatively high bioavailability. Its chemical structure includes a 17β-hydroxy-11β-(4-dimethylaminophenyl)-18-oxa-19-norprogesterone framework, which contributes to its biological activity. Mifepristone is also noted for its potential side effects, which can include gastrointestinal disturbances, fatigue, and hormonal changes. Due to its significant impact on reproductive health, mifepristone is subject to strict regulatory controls in many countries.
Formula:C29H35NO2
InChI:InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1
InChI key:InChIKey=VKHAHZOOUSRJNA-GCNJZUOMSA-N
SMILES:C[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(N(C)C)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C#CC)O)[H]
Synonyms:- (11R,13S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
- (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one
- 17β-Hydroxy-11β-[4-(dimethylamino)-phenyl]-17α-(prop-1-ynyl)-estra-4,9-dien-3-one
- C 1073
- Cdb 2477
- Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)-, (11β,17β)-
- Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-, (11β,17β)-
- MTPill
- Mifegyne
- Mifeprex
- Mifepriston Dianhydride
- Mifestone
- Pencrofton
- R 38486
- Ru 38486
- Ru 486
- Ru 486-6
- See more synonyms
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Mifepristone
CAS:Formula:C29H35NO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Green powder to crystalMolecular weight:429.60Mifepristone
CAS:Adrenal cortical hormones and their derivatives nesoiFormula:C29H35NO2Color and Shape:Yellow PowderMolecular weight:429.26678Mifepristone
CAS:Mifepristone (C-1073) is a progesterone-receptor (IC50=0.2 nM) and glucocorticoid-receptor antagonist (IC50=2.6 nM). High-Quality, Low-Cost!Formula:C29H35NO2Purity:98.9% - ≥95%Color and Shape:SolidMolecular weight:429.5937Mifepristone
CAS:MifepristoneFormula:C29H35NO2Purity:>98%Color and Shape:SolidMolecular weight:429.59Mifepristone
CAS:Formula:C29H35NO2Purity:≥ 98.0%Color and Shape:Off-white to pale yellow or yellow powderMolecular weight:429.59Mifepristone 1.0 mg/ml in Acetonitrile
CAS:Formula:C29H35NO2Color and Shape:ColourlessMolecular weight:429.59(11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one
CAS:Formula:C29H35NO2Purity:98%Color and Shape:SolidMolecular weight:429.5937Ref: IN-DA00359Q
100mg24.00€250mg25.00€1g34.00€5g82.00€10g116.00€25g205.00€50g343.00€100g601.00€250g754.00€500g1,318.00€1kg1,922.00€Mifepristone-d3
CAS:Controlled ProductApplications A labelled progesterone receptor antagonist with partial agonist activity. Abortifacient.
References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)Formula:C29D3H32NO2Color and Shape:NeatMolecular weight:432.6122Mifepristone
CAS:Controlled ProductApplications Mifepristone is a progesterone receptor antagonist with partial agonist activity. Abortifacient.
References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)Formula:C29H35NO2Color and Shape:NeatMolecular weight:429.59
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