CAS 84380-01-8

α-Arbutin

Description:

α-Arbutin is a naturally occurring glycosylated hydroquinone, primarily derived from the bearberry plant, and is known for its skin-lightening properties. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C12H16O7. The compound functions as a tyrosinase inhibitor, which helps to reduce melanin production in the skin, making it popular in cosmetic formulations aimed at treating hyperpigmentation and uneven skin tone. α-Arbutin is considered more stable and effective than its counterpart, β-arbutin, and is often used in concentrations ranging from 0.5% to 2% in various skincare products. In addition to its cosmetic applications, α-arbutin is also noted for its antioxidant properties, contributing to skin health by combating oxidative stress. Safety assessments indicate that it is generally regarded as safe for topical use, although individual sensitivities may vary. Overall, α-arbutin is valued in the beauty industry for its efficacy and stability in skin care formulations.

Formula: C₁₂H₁₆O₇

InChI: InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChI key: InChIKey=BJRNKVDFDLYUGJ-ZIQFBCGOSA-N

SMILES: O([C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=CC=C(O)C=C2

Synonyms:

• 4-Hydroquinone-alpha-D-glucopyranoside
• 4-Hydroxyphenyl α-<span class="text-smallcaps">D</span>-glucopyranoside
• 4-hydroxyphenyl alpha-D-glucopyranoside
• Hydroquinone O-α-<span class="text-smallcaps">D</span>-glucopyranoside
• a-Arbutin
• α-<span class="text-smallcaps">D</span>-Glucopyranoside, 4-hydroxyphenyl
• α-D-Glucopyranoside, 4-hydroxyphenyl
• Hydroquinone O-α-D-glucopyranoside
• 4-Hydroxyphenyl α-D-glucopyranoside

α-Arbutin

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Purity: >95.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 272.25

Ref: 3B-A3284

a-D-Glucopyranoside, 4-hydroxyphenyl

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Purity: %

Color and Shape: Solid

Molecular weight: 272.2512

Ref: IN-DA00IDDG

α-Arbutin

CAS: 84380-01-8

α-Arbutin

Purity: 99%

Molecular weight: 272.25g/mol

Ref: 54-OR1012255

α-Arbutin

CAS: 84380-01-8

α-Arbutin

Purity: ≥98%

Molecular weight: 272.25g/mol

Ref: 54-BUP11724

α-Arbutin

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Molecular weight: 272.26

Ref: 4Z-A-132001

α-Arbutin

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 272.25

Ref: 7W-GC6524

α-Arbutin

CAS: 84380-01-8

α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.

Formula: C₁₂H₁₆O₇

Purity: 99.82% - 99.94%

Color and Shape: Solid Powder

Molecular weight: 272.25

Ref: TM-T4911

alpha-Arbutin

Controlled Product

CAS: 84380-01-8

Applications α-Arbutin is a component used in the skin-whitening cosmetics.
References Magnusson, B., et al.: J. Invest. Dermatol., 52, 268 (1969), Goodwin, B., et al.: Contact Dermatitis, 7, 248, (1981), ,Itoh, M., et al.: J. Dermatol., 9, 223 (1982), Sugimoto, K., et al.: Biol. Pharm. Bull., 24, 510 (2004),

Formula: C₁₂H₁₆O₇

Color and Shape: Neat

Molecular weight: 272.25

Ref: TR-A766500

4-Hydroxyphenyl a-D-glucopyranoside

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Purity: 95.0%

Color and Shape: Solid, White powder

Molecular weight: 272.253

Ref: 10-F215658

α-Arbutin

CAS: 84380-01-8

Formula: C₁₂H₁₆O₇

Molecular weight: 272.25

Ref: ST-EA-CP-A210001

a-Arbutin

CAS: 84380-01-8

Arbutin or alpha-arbutin is a natural product. It is a hydroquinone glucoside with antioxidant properties. It is widely used in cosmetics as depigmenting agent, acting as an inhibitor of tyrosinase in melanocytes. Arbutin acts by supressing the enzymes that stimulate these melanocytes without killing or fully inhibiting them. As a consequence, melanin production is decreased to avoid hyperpigmentation that might be caused by an excess of UV radiation or a higher activity of tyrosinases.

Formula: C₁₂H₁₆O₇

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 272.25 g/mol

Ref: 3D-EA10634