CAS 84380-01-8: α-Arbutin
Description:α-Arbutin is a naturally occurring glycosylated hydroquinone, primarily derived from the bearberry plant, and is known for its skin-lightening properties. It is a white to off-white crystalline powder that is soluble in water and has a molecular formula of C12H16O7. The compound functions as a tyrosinase inhibitor, which helps to reduce melanin production in the skin, making it popular in cosmetic formulations aimed at treating hyperpigmentation and uneven skin tone. α-Arbutin is considered more stable and effective than its counterpart, β-arbutin, and is often used in concentrations ranging from 0.5% to 2% in various skincare products. In addition to its cosmetic applications, α-arbutin is also noted for its antioxidant properties, contributing to skin health by combating oxidative stress. Safety assessments indicate that it is generally regarded as safe for topical use, although individual sensitivities may vary. Overall, α-arbutin is valued in the beauty industry for its efficacy and stability in skin care formulations.
Formula:C12H16O7
InChI:InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
InChI key:InChIKey=BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
SMILES:OC1=CC=C(OC2OC(CO)C(O)C(O)C2O)C=C1
- Synonyms:
- 4-Hydroquinone-alpha-D-glucopyranoside
- 4-Hydroxyphenyl α-<span class="text-smallcaps">D</span>-glucopyranoside
- 4-hydroxyphenyl alpha-D-glucopyranoside
- Hydroquinone O-α-<span class="text-smallcaps">D</span>-glucopyranoside
- a-Arbutin
- α-<span class="text-smallcaps">D</span>-Glucopyranoside, 4-hydroxyphenyl
- α-D-Glucopyranoside, 4-hydroxyphenyl
- Hydroquinone O-α-D-glucopyranoside
- 4-Hydroxyphenyl α-D-glucopyranoside
