CAS 844499-71-4

4-Hydroxy-3-(2'-hydroxy-1,1'-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile

Description:

4-Hydroxy-3-(2'-hydroxy-1,1'-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile is a complex organic compound characterized by its unique structural features, including a thieno[2,3-b]pyridine core, hydroxyl groups, and a carbonitrile functional group. This compound exhibits a range of chemical properties due to the presence of multiple functional groups, which can influence its reactivity and solubility. The hydroxyl groups contribute to its potential for hydrogen bonding, enhancing solubility in polar solvents. The carbonitrile group may impart additional reactivity, making it a candidate for various chemical transformations. Its thieno[2,3-b]pyridine framework suggests potential biological activity, as many compounds with similar structures have been investigated for pharmacological properties. The compound's molecular complexity may also lead to interesting electronic properties, making it a subject of interest in materials science and organic electronics. Overall, this substance's unique combination of functional groups and structural motifs positions it as a potentially valuable compound in both synthetic chemistry and medicinal applications.

Formula: C₂₀H₁₂N₂O₃S

Synonyms:

• A 769662
• A769662
• Thieno[2,3-b]pyridine-5-carbonitrile,6,7-dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-

4-Hydroxy-3-(2'-hydroxy-1,1'-biphenyl-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile

CAS: 844499-71-4

Formula: C₂₀H₁₂N₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 360.3859

Ref: IN-DA0038EQ

A-769662

CAS: 844499-71-4

A-769662

Purity: ≥95%

Molecular weight: 360.39g/mol

Ref: 54-BUP12939

4,6-Dihydroxy-3-(2’-Hydroxy-[1,1’-Biphenyl]-4-Yl)Thieno[2,3-B]Pyridine-5-Carbonitrile

CAS: 844499-71-4

4,6-Dihydroxy-3-(2’-Hydroxy-[1,1’-Biphenyl]-4-Yl)Thieno[2,3-B]Pyridine-5-Carbonitrile

Purity: 98%

Molecular weight: 360.39g/mol

Ref: 54-OR1011353

A-769662

CAS: 844499-71-4

A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).

Formula: C₂₀H₁₂N₂O₃S

Purity: 97.52% - 99.58%

Color and Shape: Solid

Molecular weight: 360.39

Ref: TM-T2468

A-769662

CAS: 844499-71-4

Formula: C₂₀H₁₂N₂O₃S

Molecular weight: 360.39

Ref: 7W-GE5380

A 769662

CAS: 844499-71-4

Allosteric activator of AMP-activated protein kinase (AMPK) acting on the AMPK-β subunit with therapeutic potential in metabolic disorders such as diabetes, obesity, etc. A769662 also blocks the differentiation of mouse embryonic stem cells (mESCs) and maintains the mESCs in naïve state even in the absence of leukemia inhibitory factor (2i/L).

Formula: C₂₀H₁₂N₂O₃S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 360.39 g/mol

Ref: 3D-FA16147

A 769662

Controlled Product

CAS: 844499-71-4

Applications A 769662 is an AMP-activated protein kinase (AMPK) activiator. A 769662 selectively activates cardiac AMPK heterotrimeric complexes contg. α2/β1-subunits.
References Timmermans, A.D., et. al.: Am. J. Phys., 306, H1619 (2014)

Formula: C₂₀H₁₂N₂O₃S

Color and Shape: Neat

Molecular weight: 360.39

Ref: TR-A101205