CAS 844639-07-2

Formula: C23H27N3O3S

InChI: InChI=1S/C23H27N3O3S/c1-18(27)29-17-16-28-15-14-25-10-12-26(13-11-25)23-19-6-2-4-8-21(19)30-22-9-5-3-7-20(22)24-23/h2-9H,10-17H2,1H3

InChI key: PBAGNAROQHNFON-UHFFFAOYSA-N

SMILES: CC(=O)OCCOCCN1CCN(CC1)C2=NC3=CC=CC=C3SC4=CC=CC=C42

Quetiapine EP Impurity A DiHCl (Quetiapine O-Acetyl Impurity DiHCl)

CAS: 844639-07-2

Formula: C₂₃H₂₇N₃O₃S·2HCl

Color and Shape: Pale Yellow Solid

Molecular weight: 425.55 2*36.46

Ref: 4Z-Q-0126

Quetiapine impurity 21

CAS: 844639-07-2

Quetiapine impurity 21 is an impurity of Quetiapine.

Formula: C₂₃H₂₇N₃O₃S

Molecular weight: 425.54

Ref: TM-TYD-09436

Quetiapine EP Impurity A

CAS: 844639-07-2

Formula: C₂₃H₂₇N₃O₃S

Molecular weight: 425.54

Ref: ST-EA-CP-Q1001

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl AcetateQuetiapine Acetate

Controlled Product

CAS: 844639-07-2

Impurity Quetiapine Impurity B; Quetiapine USP-B; EP Impurity A
Applications 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl Acetate (Quetiapine Impurity B; Quetiapine USP-B) is an impurity of Quetiapine Hemifumarate (Q510000), an antipsychotic.
References Kumar, K.S., et. al.: Org. Chem., 8, 164 (2012)

Formula: C₂₃H₂₇N₃O₃S

Color and Shape: Neat

Molecular weight: 425.5438

Ref: TR-D417095

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl-d8)ethoxy)ethyl Acetate

Controlled Product

CAS: 844639-07-2

Formula: C₂₃D₈H₁₉N₃O₃S

Color and Shape: Neat

Molecular weight: 433.593

Ref: TR-D417097

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl acetatequetiapine acetate

CAS: 844639-07-2

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl acetatequetiapine acetate is a drug product that is synthesized and purified by HPLC. It is a metabolite of quetiapine, an antipsychotic drug used for the treatment of schizophrenia and bipolar disorder. 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl acetatequetiapine acetate has been shown to be more potent than quetiapine in inhibiting dopamine release in rat brain synaptosomes and dopamine transporter activity in human cells. This compound also inhibits the binding of ligands to the serotonin transporter at higher concentrations than those required for inhibition of dopamine uptake.

Formula: C₂₃H₂₇N₃O₃S

Purity: Min. 95%

Molecular weight: 425.50 g/mol

Ref: 3D-UIB63907