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CAS 84467-94-7

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Desmethylsibutramine hydrochloride

Description:
Desmethylsibutramine hydrochloride is a chemical compound that is a derivative of sibutramine, which was originally developed as an appetite suppressant for weight loss. This substance is characterized by its molecular structure, which includes a central amine group, contributing to its pharmacological activity. Desmethylsibutramine is known to act as a serotonin-norepinephrine reuptake inhibitor, influencing neurotransmitter levels in the brain, which can affect mood and appetite. The hydrochloride salt form enhances its solubility in water, making it more bioavailable for potential therapeutic applications. However, it is important to note that desmethylsibutramine and its parent compound have been associated with various side effects, including cardiovascular risks, leading to regulatory scrutiny and withdrawal from the market in many regions. As a result, its use is often limited and subject to strict regulations. Safety and efficacy assessments are crucial for any potential therapeutic use, and ongoing research is necessary to fully understand its pharmacological profile and implications for human health.
Formula:C16H24ClN·ClH
InChI:InChI=1S/C16H24ClN.ClH/c1-12(2)11-15(18-3)16(9-4-10-16)13-5-7-14(17)8-6-13;/h5-8,12,15,18H,4,9-11H2,1-3H3;1H
InChI key:InChIKey=OUVFHVJVFLFXPQ-UHFFFAOYSA-N
SMILES:C(CC(C)C)(NC)C1(CCC1)C2=CC=C(Cl)C=C2.Cl
Synonyms:
  • 1-(1-(4-Chlorophenyl)cyclobutyl)-N,3-dimethylbutan-1-amine hydrochloride
  • Bts 54-354
  • Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride
  • Cyclobutanemethanamine,1-(4-chlorophenyl)-N-methyl-a-(2-methylpropyl)-, hydrochloride (9CI)
  • Desmethylsibutramine hydrochloride
  • Desmethylsibutraminehydrochloride
  • Cyclobutanemethanamine, 1-(4-chlorophenyl)-N-methyl-α-(2-methylpropyl)-, hydrochloride (1:1)
Found 12 products.