Biosynth

3'-Amino-2',3'-dideoxyuridine (CAS 84472-86-6) is a nucleoside analog that plays a significant role in biochemical research and pharmaceutical applications. It is characterized by the presence of an amino group at the 3' position and lacks the hydroxyl groups typically found in the ribose sugar of standard nucleosides, which contributes to its dideoxy nature. This structural modification enhances its stability and resistance to nucleases, making it a valuable tool in molecular biology, particularly in studies involving DNA synthesis and antiviral drug development. The compound exhibits potential antiviral activity, particularly against certain viruses, by interfering with viral replication processes. Additionally, its unique structure allows it to be incorporated into nucleic acids, which can lead to chain termination during DNA synthesis. Overall, 3'-amino-2',3'-dideoxyuridine is an important compound in the field of medicinal chemistry and virology, providing insights into nucleic acid interactions and therapeutic strategies.

3'-amino-2',3'-dideoxyuridine

84472-86-6: 3'-Amino-2',3'-dideoxyuridine (CAS 84472-86-6) is a nucleoside analog that plays a significant role in biochemical research and pharmaceutical applications. It is characterized by the presence of an amino group at the 3' position and lacks the hydroxyl groups typically found in the ribose sugar of standard nucleosides, which contributes to its dideoxy nature. This structural modification enhances its stability and resistance to nucleases, making it a valuable tool in molecular biology, particularly in studies involving DNA synthesis and antiviral drug development. The compound exhibits potential antiviral activity, particularly against certain viruses, by interfering with viral replication processes. Additionally, its unique structure allows it to be incorporated into nucleic acids, which can lead to chain termination during DNA synthesis. Overall, 3'-amino-2',3'-dideoxyuridine is an important compound in the field of medicinal chemistry and virology, providing insights into nucleic acid interactions and therapeutic strategies.

<p>3'-Amino-2',3'-dideoxyuridine (3'ADU) is an nucleoside analog that inhibits the growth of tumor cells by blocking the enzymatic reaction required for DNA synthesis. 3'ADU has been shown to be effective in treating immunodeficiency, and has been shown to inhibit the proliferation of cervical cancer cells. 3'ADU also inhibits HIV-1 replication in cultured lymphocytes, but does not affect the viral load in a rat liver microsome assay.<br><br>The 6-fluoro-3-indoxyl-beta-D-galactopyranoside is a potent antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis and is metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction</p>

CAS 84472-86-6

3'-amino-2',3'-dideoxyuridine

3'-Amino-2',3'-dideoxyuridine

Ref: 3D-FA152375