CAS 84499-45-6

Formula: C13H13Cl2N3O3

InChI: InChI=1S/C13H13Cl2N3O3/c14-9-1-2-11(12(15)3-9)13(6-18-7-16-17-8-18)20-5-10(4-19)21-13/h1-3,7-8,10,19H,4-6H2/t10-,13-/m0/s1

InChI key: SROVJWXKOIHEMR-GWCFXTLKSA-N

SMILES: C1[C@@H](O[C@@](O1)(CN2C=NN=C2)C3=C(C=C(C=C3)Cl)Cl)CO

Itraconazole Impurity 34

CAS: 84499-45-6

Formula: C₁₃H₁₃Cl₂N₃O₃

Molecular weight: 330.17

Ref: 4Z-I-0360

cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol

Controlled Product

CAS: 84499-45-6

Applications cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol is an impurity in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazol.
References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)

Formula: C₁₃H₁₃Cl₂N₃O₃

Color and Shape: Neat

Molecular weight: 330.17

Ref: TR-D436341

Itraconazole Impurity 34

CAS: 84499-45-6

Formula: C₁₃H₁₃Cl₂N₃O₃

Molecular weight: 330.17

Ref: ST-EA-CP-I3046