CAS 845306-08-3

tert-butyl 5-bromopyridine-2-carboxylate

Description:

Tert-butyl 5-bromopyridine-2-carboxylate is an organic compound characterized by its pyridine ring, which is substituted at the 5-position with a bromine atom and at the 2-position with a carboxylate group. The tert-butyl group enhances its lipophilicity and steric hindrance, making it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. This compound typically exhibits moderate to high stability under standard conditions, although it may be sensitive to strong acids or bases, which can lead to hydrolysis of the ester functional group. Its solubility is generally higher in organic solvents compared to water, reflecting its hydrophobic nature. The presence of the bromine atom can also facilitate various reactions, such as nucleophilic substitutions or coupling reactions, making it a versatile building block in synthetic chemistry. Additionally, the compound's structure allows for potential applications in medicinal chemistry, where modifications can lead to biologically active derivatives.

Formula: C₁₀H₁₂BrNO₂

InChI: InChI=1/C10H12BrNO2/c1-10(2,3)14-9(13)8-5-4-7(11)6-12-8/h4-6H,1-3H3

InChI key: GBAJDPJECJPPSP-UHFFFAOYSA-N

SMILES: CC(C)(C)OC(=O)c1ccc(cn1)Br

tert-Butyl 5-bromopyridine-2-carboxylate

CAS: 845306-08-3

tert-Butyl 5-bromopyridine-2-carboxylate

Formula: C₁₀H₁₂BrNO₂

Purity: 0.97

Color and Shape: Solid

Molecular weight: 258.11177

Ref: 54-OR3355

2-Pyridinecarboxylic acid, 5-bromo-, 1,1-dimethylethyl ester

CAS: 845306-08-3

Formula: C₁₀H₁₂BrNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 258.1118

Ref: IN-DA008HVE

tert-Butyl 5-bromopicolinate

CAS: 845306-08-3

tert-Butyl 5-bromopicolinate

Formula: C₁₀H₁₂BrNO₂

Purity: 97%

Molecular weight: 258.11

Ref: IN-DG218127

tert-Butyl 5-bromopicolinate

CAS: 845306-08-3

Formula: C₁₀H₁₂BrNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 258.115

Ref: 10-F231107

tert-Butyl 5-bromopyridine-2-carboxylate

CAS: 845306-08-3

tert-Butyl 5-bromopyridine-2-carboxylate is an arylation agent that is used to synthesize a number of different compounds. It is the most potent arylating agent known, with high yields and low toxicity. The benzyl group provides protection against hydrogen chloride and can be removed by hydrolysis. This agent reacts with a variety of aromatic halides in the presence of copper salts to produce a variety of products. Tert-Butyl 5-bromopyridine-2-carboxylate has been shown to have good pharmacokinetic properties, but it's use as an antibiotic has not been studied.

Formula: C₁₀H₁₂BrNO₂

Purity: Min. 95%

Molecular weight: 258.11 g/mol

Ref: 3D-VIB30608