CAS 84611-23-4

Erdosteine

Description:

Erdosteine is a synthetic compound primarily used as a mucolytic agent, which means it helps to break down and thin mucus in the respiratory tract, making it easier to expel. It is classified as a thiol derivative and is known for its ability to enhance mucociliary clearance, thereby improving respiratory function in conditions characterized by excessive mucus production, such as chronic obstructive pulmonary disease (COPD) and bronchitis. Erdosteine exhibits antioxidant properties, which may contribute to its therapeutic effects by reducing oxidative stress in the lungs. The compound is typically administered orally and is well-absorbed, with a favorable safety profile. Its mechanism of action involves the cleavage of disulfide bonds in mucus, leading to a reduction in viscosity. Erdosteine is also noted for its potential to modulate inflammatory responses, further supporting its use in respiratory conditions. Overall, it is recognized for its dual role as a mucolytic and an antioxidant, making it a valuable option in respiratory therapy.

Formula: C₈H₁₁NO₄S₂

InChI: InChI=1S/C8H11NO4S2/c10-6(3-14-4-7(11)12)9-5-1-2-15-8(5)13/h5H,1-4H2,(H,9,10)(H,11,12)

InChI key: InChIKey=QGFORSXNKQLDNO-UHFFFAOYSA-N

SMILES: N(C(CSCC(O)=O)=O)C1C(=O)SCC1

Synonyms:

• (+/-)-((((Tetrahydro-2-oxo-3-thienyl)carbamoyl)methyl)thio)acetic acid
• ({2-Oxo-2-[(2-Oxotetrahydrothiophen-3-Yl)Amino]Ethyl}Sulfanyl)Acetic Acid
• 2-([[(2-Oxothiolan-3-yl)carbamoyl]methyl]sulfanyl)acetic acid
• 2-[2-Oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid
• 2-[[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]acetic acid
• Acetic acid, ((2-oxo-2-((tetrahydro-2-oxo-3-thienyl)amino)ethyl)thio)-
• Acetic acid, 2-[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]-
• Acide ((2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio)acetique
• Acide ((2-oxo-3-tetrahydrothienylcarbamoyl)-methylthio)acetique [French]
• DL-S-(2-(N-3-(2-Oxotetrahydrotheinyl)acetamido))thioglycolic acid
• Dithiosteine
• Erdosteinum
• Erdostin
• Mucotec
• Rv 144
• Secresolv
• [[2-Oxo-2-[(Tetrahydro-2-Oxo-3-Thienyl)Amino]Ethyl]Thio]Acetic Acid

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 249.30

Ref: 3B-E1026

Erdosteine

CAS: 84611-23-4

Erdosteine

Formula: C₈H₁₁NO₄S₂

Purity: 98%

Molecular weight: 249.31

Ref: 54-OR1027175

Erdosteine

CAS: 84611-23-4

Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.

Formula: C₈H₁₁NO₄S₂

Purity: 99.65% - 99.94%

Color and Shape: White Solid

Molecular weight: 249.31

Ref: TM-T1229

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Color and Shape: White To Off-White Solid

Molecular weight: 249.30

Ref: 4Z-E-085001

Erdosteine

CAS: 84611-23-4

Erdosteine

Formula: C₈H₁₁NO₄S₂

Purity: 99.5%

Molecular weight: 249.31

Ref: 54-BUP16886

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Molecular weight: 249.31

Ref: 7W-GP7165

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Color and Shape: Neat

Molecular weight: 249.31

Ref: 86-MM0544.00

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 249.3072

Ref: IN-DA003PY1

Erdosteine

Controlled Product

CAS: 84611-23-4

Applications Erdosteine is a mucolytic. Erdosteine was developed for the treatment of chronic obstructive bronchitis.
References Kuvandik, G., et al.: Toxicol. Pathol., 36, 714 (2008), Koyu, A., et al.: Mol. Cell. Biochem., 331, 43 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010),

Formula: C₈H₁₁NO₄S₂

Color and Shape: Neat

Molecular weight: 249.31

Ref: TR-E596050

Erdosteine

CAS: 84611-23-4

2-((2-Oxo-2-((2-oxotetrahydrothiophen-3-yl)amino)ethyl)thio)acetic acid

Formula: C₈H₁₁NO₄S₂

Purity: 98%

Molecular weight: 249.31

Ref: IN-DG127439

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Molecular weight: 249.30

Ref: ST-EA-CP-E38000

Erdosteine

CAS: 84611-23-4

Erdosteine is a reactive molecule that is generated in the reaction solution and has been shown to have pro-apoptotic properties. It has been shown to protect against oxidative injury as it can react with reactive oxygen species, such as peroxynitrite, by converting them into less harmful molecules. Erdosteine also protects against neuronal death induced by 3-nitropropionic acid, which is a neurotoxin that inhibits mitochondrial respiratory chain complex I. Erdosteine may be used for the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The side-effect profiles of erdosteine are not well understood and more research needs to be done in order to determine if this drug could be used therapeutically.

Formula: C₈H₁₁NO₄S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 249.31 g/mol

Ref: 3D-FE22779

Erdosteine

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Molecular weight: 249.3

Ref: BE-RMCE102000

Erdosteine Metabolite 1, disodium salt-[13C4]

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Molecular weight: 249.3

Ref: BE-MC-7806

Erdosteine-[13C4]

CAS: 84611-23-4

Formula: C₈H₁₁NO₄S₂

Molecular weight: 249.3

Ref: BE-MC-7805

ERDOSTEINE

CAS: 84611-23-4

Purity: 98%

Molecular weight: 249.3000031

Ref: 10-F828374

Erdosteine-d4

Controlled Product

CAS: 84611-23-4

Applications Erdosteine-d4 is the isotope labelled analog of Erdosteine (E596050); a mucolytic developed for the treatment of chronic obstructive bronchitis.
References Kuvandik, G., et al.: Toxicol. Pathol., 36, 714 (2008); Koyu, A., et al.: Mol. Cell. Biochem., 331, 43 (2009); Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010)

Formula: C₈H₇D₄NO₄S₂

Color and Shape: Neat

Molecular weight: 253.33

Ref: TR-E596052