CAS 84625-61-6

Itraconazole

Description:

Itraconazole is a triazole antifungal agent primarily used to treat various fungal infections, including those caused by dermatophytes, yeasts, and certain molds. It functions by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Itraconazole is characterized by its relatively low solubility in water but is more soluble in organic solvents, which influences its bioavailability. The compound has a molecular formula of C35H38Cl2N8O4S and features a complex structure that includes a triazole ring. It is typically administered orally or intravenously, with its pharmacokinetics influenced by factors such as food intake and pH levels. Itraconazole is known for its broad spectrum of activity against various fungi, but it may also interact with other medications due to its effects on liver enzymes. Common side effects can include gastrointestinal disturbances, liver enzyme elevations, and potential cardiovascular effects, necessitating monitoring during treatment.

Formula: C₃₅H₃₈Cl₂N₈O₄

InChI: InChI=1/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/s2

InChI key: InChIKey=VHVPQPYKVGDNFY-WGEGMAFPNA-N

SMILES: C([C@]1(O[C@@H](COC2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)N5C(=O)N(C(CC)C)N=C5)CO1)C6=C(Cl)C=C(Cl)C=C6)N7C=NC=N7

Synonyms:

• 2-Butan-2-Yl-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-Yl Methyl)-1,3-Dioxolan-4-Yl]Methoxy]Phenyl]Piperazin-1-Yl]Phenyl]-1,2,4-Triazol-3-One
• 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-
• 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-
• Candistat
• Canditral
• Cladosal 100
• Fungitraxx
• Itrac
• Itraconozole
• Itralek
• Itrizole
• Oriconazole
• Orungal
• Orungamin
• Pur 1900
• R 51211
• SUBA Itraconazole
• Sempera
• Spherazole CR
• Spherazole IR
• Sporal
• Sporamelt
• Sporanox
• Sporanox IV
• Sporonox
• Traconal
• Triasporin
• cis-Itraconazole
• rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Itraconazole, 98%

CAS: 84625-61-6

Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: 98%

Color and Shape: White to cream, Powder or crystalline powder

Molecular weight: 705.64

Ref: 02-J66390

Itraconazole

CAS: 84625-61-6

Color and Shape: Neat

Ref: 61-FOR0258.00

Itraconazole 2.0 mg/ml in Dimethyl Sulfoxide

CAS: 84625-61-6

Color and Shape: Single Solution

Ref: 61-AMP0258.00-36

ITRACONAZOLE CRS

CAS: 84625-61-6

ITRACONAZOLE CRS

Formula: C₃₅H₃₈Cl₂N₈O₄

Color and Shape: White. Powder.

Molecular weight: 705.6334

Ref: 41-I7000000

Itraconazole

CAS: 84625-61-6

Itraconazole

Formula: C₃₅H₃₈CI₂N₈O₄

Purity: 99.7%

Color and Shape: White To Off-White

Molecular weight: 900.11055

Ref: 47-1199

ITRACONAZOLE FOR SYSTEM SUITABILITY CRS

CAS: 84625-61-6

ITRACONAZOLE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001100

Itraconazole

CAS: 84625-61-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₃₅H₃₈ClN₈O₄

Color and Shape: White Powder

Molecular weight: 669.27045

Ref: 45-1354251

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 705.6334

Ref: IN-DA003R60

Itraconazole

CAS: 84625-61-6

Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: 98% - 99.90%

Color and Shape: Off-White Crystalline Solid

Molecular weight: 705.63

Ref: TM-T1011

Itraconazole

CAS: 84625-61-6

Itraconazole

Purity: ≥98%

Molecular weight: 705.63g/mol

Ref: 54-BUP15992

Itraconazole-d3

CAS: 84625-61-6

Formula: C₃₅H₃₅D₃Cl₂N₈O₄

Color and Shape: Off-White Solid

Molecular weight: 708.67

Ref: 4Z-I-032

Itraconazole-d9

CAS: 84625-61-6

Formula: C₃₅H₂₉D₉Cl₂N₈O₄

Color and Shape: Off-White Solid

Molecular weight: 714.70

Ref: 4Z-I-036

Itraconazole Impurity 5

CAS: 1217510-38-7, 84625-61-6

Formula: C₃₄H₃₅Cl₂N₈O₄·Cl

Color and Shape: Yellow Solid

Molecular weight: 690.61 35.45

Ref: 4Z-I-0331

Itraconazole N-Oxide

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₅

Color and Shape: White To Off-White Solid

Molecular weight: 721.64

Ref: 4Z-I-0329

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: 99.0 - 101.0 % (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 705.63

Ref: 7W-GA0307

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Color and Shape: White To Off-White Solid

Molecular weight: 705.64

Ref: 4Z-I-031

Itraconazole

CAS: 84625-61-6

Itraconazole

Purity: 98%

Molecular weight: 705.63g/mol

Ref: 54-OR1029174

Itraconazole

CAS: 84625-61-6

Color and Shape: Neat

Ref: 86-MM0258.00

Itraconazole

Controlled Product

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Color and Shape: Neat

Molecular weight: 705.63

Ref: 04-C14485000

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 705.64

Ref: 3B-I0732