CAS 84676-89-1
:Astragaloside II
Description:
Astragaloside II, with the CAS number 84676-89-1, is a natural glycoside primarily derived from the root of Astragalus membranaceus, a plant commonly used in traditional medicine. This compound is characterized by its structural composition, which includes a sugar moiety linked to a steroidal aglycone. Astragaloside II is known for its potential pharmacological properties, including immunomodulatory, anti-inflammatory, and antioxidant effects. It has been studied for its role in enhancing immune function and promoting cellular health. Additionally, research suggests that it may have protective effects against oxidative stress and could support cardiovascular health. The compound is typically soluble in polar solvents, and its stability can be influenced by factors such as pH and temperature. As a bioactive compound, Astragaloside II is of interest in both pharmacological research and herbal medicine, although further studies are needed to fully elucidate its mechanisms of action and therapeutic potential.
Formula:C43H70O15
InChI:InChI=1/C43H70O15/c1-21(45)54-29-28(48)23(47)19-53-34(29)58-43(52)32(49)25(18-44)56-35(33(43)50)55-24-16-26-39(7)17-22(46)30(40(8)13-10-27(57-40)37(4,5)51)38(39,6)14-15-41(26)20-42(41)12-9-11-36(2,3)31(24)42/h22-35,44,46-52H,9-20H2,1-8H3/t22-,23+,24-,25+,26?,27-,28-,29+,30-,31?,32+,33-,34-,35+,38+,39-,40+,41?,42+,43+/m0/s1
InChI key:InChIKey=AYWNHWGQTMCQIV-PENCHUSISA-N
SMILES:C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](OC(C)=O)[C@@H](O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]
Synonyms:- (2S,3R,4S,5R)-4,5-dihydroxy-2-{[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-2-({(1R,2S,3aS,5S,9aR,12aR)-2-hydroxy-1-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl]-3a,6,6,12a-tetramethyltetradecahydro-1H-cyclopenta[a]cyclopropa[e]phenanthren-5-yl}oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}tetrahydro-2H-pyran-3-yl acetate (non-preferred name)
- (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-<span class="text-smallcaps">D</smallcap>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
- 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
- 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
- Astrasieversianin VIII
- NSC 641295
- astragalosideⅡ
- β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-<smallcap>D</span>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
- 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-D-glucopyranoside deriv.
- (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
- Astragaloside II
- 9,19-Cyclolanostane, β-D-glucopyranoside deriv.
- β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
- Astragaloside II
- (3b,6a,16b,20r,24s)-3-((2-o-acetyl-beta-d-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-d-glucopyranoside
- Astragaloside II USP/EP/BP
- Cyclosiversioside D
- Astragaloside II 84676-89-1
- Astragaloside II (Astrasieversianin VIII)
- Astragaloside B
- 16,25-dihydroxy-9,19-cyclolanostan-6-yl
- Astragalin Astragaloside II
- Cyclosieversioside D
- ASTRAGALOSIDE II(SH)
- 3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-
- See more synonyms
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Astragaloside II (Standard)
CAS:Astragaloside II (Standard) is a reference standard for research and analysis in studies involving Astragaloside II. Astragaloside II (Astrasieversianin VIII) is an effective MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Astragaloside II also induces osteogenic activities, differentiation, proliferation, and mineralization, through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.Formula:C43H70O15Molecular weight:827.0069Astragaloside II
CAS:Astragaloside II can downregulate the expression of the P-gp and mdr1 gene, suppress phosphorylation of extracellular signal regulated kinase 1/2, p38 and c-Jun N-terminal kinase, suggests that Astragaloside II is a potent multidrug resistance (MDR) reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.Formula:C43H70O15Purity:95%~99%Color and Shape:PowderMolecular weight:827.018Astragaloside II
CAS:Controlled ProductApplications Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. Used in the prevention of cardio-cerebral vascular diseases.
References Shaw, L et al.: PLoS One, 7, e3848 (2012); Kong, X. et al.: Int. J. Mol. Med., 29, 1090 (2012);Formula:C43H70O15Color and Shape:NeatMolecular weight:827.01Astragaloside II
CAS:Astragaloside II: Potent for MDR, hepatic cancer therapy; boosts osteogenesis via BMP-2/MAPK, Smad1/5/8 pathways.Formula:C43H70O15Purity:98.54% - 99.7%Color and Shape:White SolidMolecular weight:827.0069Ref: TM-T3924
1mL*10mM (DMSO)39.00€10mg45.00€25mg85.00€50mg117.00€100mg175.00€200mg251.00€500mg429.00€Astragaloside II
CAS:Natural glycosideFormula:C43H70O15Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:827.02(2S,3R,4S,5R)-4,5-Dihydroxy-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-hydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetradecahydro-1H,12H-cyclopenta[a]cyclopropa[e]phenanthren-9-yl)oxy)tetrahydro-2H-pyran-3-yl acetate
CAS:(2S,3R,4S,5R)-4,5-Dihydroxy-2-(((2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-4-hydroxy-3-((2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethyl-7-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tFormula:C43H70O15Purity:98%Molecular weight:827.01Astragaloside II
CAS:Astragaloside II is a natural compound that has been shown to have anti-inflammatory effects in vitro and in vivo. Astragaloside II inhibits the production of inflammatory mediators by inhibiting phosphodiesterase and cyclooxygenase pathways. It also has a matrix effect on the cells, which may be due to its ability to activate protein kinase C. This compound also has an analytical method, which consists of HPLC with UV detection at 210 nm.
Formula:C43H70O15Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:827.01 g/molβ-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
CAS:Formula:C43H70O15Purity:98%Color and Shape:SolidMolecular weight:827.0069










